ENSMUSG00000047030


Mus musculus

Features
Gene ID: ENSMUSG00000047030
  
Biological name :Spata2
  
Synonyms : Spata2 / spermatogenesis associated 2
  
Possible biological names infered from orthology : Q9UM82
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H3
Gene start: 167481133
Gene end: 167492887
  
Corresponding Affymetrix probe sets: 10489904 (MoGene1.0st)   1434107_at (Mouse Genome 430 2.0 Array)   1456776_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000057095
Ensembl peptide - ENSMUSP00000104834
NCBI entrez gene - 263876     See in Manteia.
MGI - MGI:2146885
RefSeq - XM_017318651
RefSeq - NM_170756
RefSeq - XM_006499586
RefSeq - XM_017318649
RefSeq - XM_017318650
RefSeq - XM_006499584
RefSeq Peptide - NP_739562
swissprot - Q3UML2
swissprot - Q8K004
Ensembl - ENSMUSG00000047030
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spata2ENSDARG00000063250Danio rerio
 SPATA2ENSGALG00000008026Gallus gallus
 Q9UM82ENSG00000158480Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BNN1 / Spata2l / spermatogenesis associated 2-like / Q8IUW3*ENSMUSG0000003359417


Protein motifs (from Interpro)
Interpro ID Name
 IPR029744  Spermatogenesis-associated protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0001650 fibrillar center ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000313 abnormal cell death "anomalous cessation of function at the cellular level" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Csgalnact1tm1Nari/Csgalnact1tm1Nari,Csgalnact2tm1.1Staka/Csgalnact2tm1.1Staka,Tg(Col2a1-cre)1Bhr/0
Genetic Background: involves: C57BL/6 * C57BL/6J * SJL

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
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Allelic Composition: Tg(MMTV-cre)1Mam/0,Tg(MMTV-PyVT)634Mul/0,Wisp3tm1.1Cgkl/Wisp3tm1.1Cgkl
Genetic Background: FVB/N-Wisp3tm1.1Cgkl Tg(MMTV-cre)1Mam Tg(MMTV-PyVT)634Mul

 MP:0001153 small seminiferous tubules "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
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Allelic Composition: Tg(MMTV-cre)1Mam/0,Tg(MMTV-PyVT)634Mul/0,Wisp3tm1.1Cgkl/Wisp3tm1.1Cgkl
Genetic Background: FVB/N-Wisp3tm1.1Cgkl Tg(MMTV-cre)1Mam Tg(MMTV-PyVT)634Mul

 MP:0001846 increased inflammatory response "greater than expected response to injury, infection, or insult " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Csgalnact1tm1Nari/Csgalnact1tm1Nari,Csgalnact2tm1.1Staka/Csgalnact2tm1.1Staka,Tg(Col2a1-cre)1Bhr/0
Genetic Background: involves: C57BL/6 * C57BL/6J * SJL

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Tg(MMTV-cre)1Mam/0,Tg(MMTV-PyVT)634Mul/0,Wisp3tm1.1Cgkl/Wisp3tm1.1Cgkl
Genetic Background: FVB/N-Wisp3tm1.1Cgkl Tg(MMTV-cre)1Mam Tg(MMTV-PyVT)634Mul

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tg(MMTV-cre)1Mam/0,Tg(MMTV-PyVT)634Mul/0,Wisp3tm1.1Cgkl/Wisp3tm1.1Cgkl
Genetic Background: FVB/N-Wisp3tm1.1Cgkl Tg(MMTV-cre)1Mam Tg(MMTV-PyVT)634Mul

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
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Allelic Composition: Tg(MMTV-cre)1Mam/0,Tg(MMTV-PyVT)634Mul/0,Wisp3tm1.1Cgkl/Wisp3tm1.1Cgkl
Genetic Background: FVB/N-Wisp3tm1.1Cgkl Tg(MMTV-cre)1Mam Tg(MMTV-PyVT)634Mul

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tg(MMTV-cre)1Mam/0,Tg(MMTV-PyVT)634Mul/0,Wisp3tm1.1Cgkl/Wisp3tm1.1Cgkl
Genetic Background: FVB/N-Wisp3tm1.1Cgkl Tg(MMTV-cre)1Mam Tg(MMTV-PyVT)634Mul

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tg(MMTV-cre)1Mam/0,Tg(MMTV-PyVT)634Mul/0,Wisp3tm1.1Cgkl/Wisp3tm1.1Cgkl
Genetic Background: FVB/N-Wisp3tm1.1Cgkl Tg(MMTV-cre)1Mam Tg(MMTV-PyVT)634Mul

 MP:0006378 abnormal spermatogonia morphology "anomaly in the number, structure or development of the large unspecialized male germ cells that give rise to spermatocytes" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tg(MMTV-cre)1Mam/0,Tg(MMTV-PyVT)634Mul/0,Wisp3tm1.1Cgkl/Wisp3tm1.1Cgkl
Genetic Background: FVB/N-Wisp3tm1.1Cgkl Tg(MMTV-cre)1Mam Tg(MMTV-PyVT)634Mul

 MP:0009647 decreased fertilization frequency "he number of secondary oocytes each penetrated by a spermatozoon followed by fusion of the male and female pronuclei are fewer than expected" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tg(MMTV-cre)1Mam/0,Tg(MMTV-PyVT)634Mul/0,Wisp3tm1.1Cgkl/Wisp3tm1.1Cgkl
Genetic Background: FVB/N-Wisp3tm1.1Cgkl Tg(MMTV-cre)1Mam Tg(MMTV-PyVT)634Mul

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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