ENSMUSG00000047631


Mus musculus

Features
Gene ID: ENSMUSG00000047631
  
Biological name :Apof
  
Synonyms : Apof / apolipoprotein F
  
Possible biological names infered from orthology : Q13790
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: D3
Gene start: 128268671
Gene end: 128270153
  
Corresponding Affymetrix probe sets: 10367221 (MoGene1.0st)   1418239_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000050300
NCBI entrez gene - 103161     See in Manteia.
MGI - MGI:104539
RefSeq - NM_133997
RefSeq Peptide - NP_598758
swissprot - A0A0R4J0M4
Ensembl - ENSMUSG00000047631
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 apofENSDARG00000090980Danio rerio
 APOFENSG00000175336Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026114  Apolipoprotein F


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005615 extracellular space IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001556 increased circulating HDL cholesterol level "higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439]
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Allelic Composition: Elavl1tm1.1Dkon/Elavl1tm1.1Dkon,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Elavl1tm1.1Dkon/Elavl1tm1.1Dkon,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Apoftm1(KOMP)Vlcg/Apof+
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0003193 decreased cholesterol efflux "reduced level of removal of excess cholesterol from cells by an active transport pathway" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
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Allelic Composition: Elavl1tm1.1Dkon/Elavl1tm1.1Dkon,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0005278 abnormal cholesterol homeostasis "anomaly in the state of equilibrium in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:71350]
Show

Allelic Composition: Elavl1tm1.1Dkon/Elavl1tm1.1Dkon,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Apoftm1(KOMP)Vlcg/Apof+
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0010027 increased liver cholesterol level "greater than normal amount in the liver of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Elavl1tm1.1Dkon/Elavl1tm1.1Dkon,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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