ENSMUSG00000048070


Mus musculus

Features
Gene ID: ENSMUSG00000048070
  
Biological name :Pirt
  
Synonyms : Phosphoinositide-interacting protein / Pirt / Q8BFY0
  
Possible biological names infered from orthology : P0C851 / phosphoinositide interacting regulator of transient receptor potential channels
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 66911981
Gene end: 66929876
  
Corresponding Affymetrix probe sets: 10376998 (MoGene1.0st)   1440581_at (Mouse Genome 430 2.0 Array)   1447493_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000128117
NCBI entrez gene - 193003     See in Manteia.
MGI - MGI:2443635
RefSeq - XM_011248822
RefSeq - NM_178656
RefSeq - XM_006532579
RefSeq Peptide - NP_848771
swissprot - Q8BFY0
Ensembl - ENSMUSG00000048070
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000029014Gallus gallus
 PIRTENSG00000233670Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR028068  Phosphoinositide-interacting protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009408 response to heat IMP
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IDA
 biological_processGO:0048266 behavioral response to pain IMP
 biological_processGO:2001259 positive regulation of cation channel activity IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IDA
 molecular_functionGO:0044325 ion channel binding IPI
 molecular_functionGO:1902936 phosphatidylinositol bisphosphate binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
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Allelic Composition: Kdm1atm1.2Tche/Kdm1atm1.2Tche
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0004811 abnormal neuron physiology "anomalous function of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Vapbtm1.1Tsud/Vapb+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0008531 increased chemical nociceptive threshold "a greater than average concentration at which chemically induced pain sensation is first detectable" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kdm1atm1.2Tche/Kdm1atm1.2Tche
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0009253 abnormal sympathetic neuron physiology "any functional anomaly of any of the neurons of the part of the autonomic nervous system that innervates smooth muscle, cardiac muscle and glands and mediates the body s response to stressful situations" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kdm1atm1.2Tche/Kdm1atm1.2Tche
Genetic Background: involves: 129/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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