ENSMUSG00000048930


Mus musculus

Features
Gene ID: ENSMUSG00000048930
  
Biological name :Tada3
  
Synonyms : Q8R0L9 / Tada3 / Transcriptional adapter 3
  
Possible biological names infered from orthology : O75528 / transcriptional adaptor 3
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: E3
Gene start: 113366025
Gene end: 113377883
  
Corresponding Affymetrix probe sets: 10546903 (MoGene1.0st)   1417467_a_at (Mouse Genome 430 2.0 Array)   1448719_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000043363
Ensembl peptide - ENSMUSP00000141289
Ensembl peptide - ENSMUSP00000108736
Ensembl peptide - ENSMUSP00000032410
NCBI entrez gene - 101206     See in Manteia.
MGI - MGI:1915724
RefSeq - XM_006505238
RefSeq - XM_006505239
RefSeq - NM_133932
RefSeq Peptide - NP_598693
swissprot - Q8R0L9
swissprot - A0A0R4J1I2
swissprot - A0A0A6YVW0
Ensembl - ENSMUSG00000048930
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tada3lENSDARG00000058220Danio rerio
 TADA3ENSGALG00000006688Gallus gallus
 TADA3ENSG00000171148Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019340  Histone acetyltransferases subunit 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IMP
 biological_processGO:0001932 regulation of protein phosphorylation IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0031063 regulation of histone deacetylation IGI
 biological_processGO:0031647 regulation of protein stability IMP
 biological_processGO:0043966 histone H3 acetylation IBA
 biological_processGO:0043967 histone H4 acetylation IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0090043 regulation of tubulin deacetylation IGI
 biological_processGO:1903506 regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0000124 SAGA complex IBA
 cellular_componentGO:0005622 intracellular ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005671 Ada2/Gcn5/Ada3 transcription activator complex ISO
 cellular_componentGO:0030914 STAGA complex ISO
 cellular_componentGO:0033276 transcription factor TFTC complex ISO
 cellular_componentGO:0072686 mitotic spindle IDA
 molecular_functionGO:0003713 transcription coactivator activity ISO
 molecular_functionGO:0004402 histone acetyltransferase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016922 nuclear receptor binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IDA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Stk39tm1.1Arte/Stk39+
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0004046 abnormal mitosis "anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Stk39tm1.1Arte/Stk39+
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0004964 absent inner cell mass "absence of the cells of the blastocyst that develop into the body of the embryo" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Stk39tm1.1Arte/Stk39+
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0010039 abnormal trophoblast giant cell proliferation "abnormality in the expansion rate of the trophoblast giant cell population by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Stk39tm1.1Arte/Stk39+
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0011095 complete embryonic lethality between implantation and placentation "death of all organisms of a given genotype in a population between the point of implantation and the initiation of placentation (Mus: E4.5 to less than E9)" [MGI:csmith]
Show

Allelic Composition: Stk39tm1.1Arte/Stk39+
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0011104 partial embryonic lethality before implantation "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Stk39tm1.1Arte/Stk39+
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0011704 decreased fibroblast proliferation "reduction in the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
Show

Allelic Composition: Stk39tm1.1Arte/Stk39+
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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