ENSMUSG00000049350


Mus musculus

Features
Gene ID: ENSMUSG00000049350
  
Biological name :Zg16
  
Synonyms : Q8K0C5 / Zg16 / zymogen granule protein 16
  
Possible biological names infered from orthology : O60844
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F3
Gene start: 127050156
Gene end: 127087328
  
Corresponding Affymetrix probe sets: 10568165 (MoGene1.0st)   1428358_at (Mouse Genome 430 2.0 Array)   1428359_s_at (Mouse Genome 430 2.0 Array)   1434137_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000145957
Ensembl peptide - ENSMUSP00000056916
Ensembl peptide - ENSMUSP00000145876
NCBI entrez gene - 69036     See in Manteia.
MGI - MGI:1916286
RefSeq - NM_026918
RefSeq - XM_006508175
RefSeq Peptide - NP_081194
swissprot - A0A0U1RPF0
swissprot - Q8K0C5
Ensembl - ENSMUSG00000049350
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ZG16ENSG00000174992Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001229  Jacalin-like lectin domain
 IPR033563  Zymogen granule membrane protein 16
 IPR036404  Jacalin-like lectin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005796 Golgi lumen ISO
 cellular_componentGO:0031012 extracellular matrix ISS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042589 zymogen granule membrane IEA
 cellular_componentGO:0060205 cytoplasmic vesicle lumen IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000477 abnormal intestine morphology "malformation of the digestive tube passing from the stomach to the anus" [J:48968]
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Allelic Composition: Pltptm2.1Jia/Pltptm2.1Jia
Genetic Background: involves: C57BL/6J

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
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Allelic Composition: Pltptm2.1Jia/Pltptm2.1Jia
Genetic Background: involves: C57BL/6J

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Pltptm2.1Jia/Pltptm2.1Jia
Genetic Background: involves: C57BL/6J

 MP:0008577 increased circulating interferon-gamma level "increase in the amount in the blood of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" [MESH:D12.644.276.374.440.893]
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Allelic Composition: Pltptm2.1Jia/Pltptm2.1Jia
Genetic Background: involves: C57BL/6J

 MP:0008596 increased circulating interleukin-6 level "increase in the amount in the blood of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts" [MESH:D12.644.276.374.465.506]
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Allelic Composition: Pltptm2.1Jia/Pltptm2.1Jia
Genetic Background: involves: C57BL/6J

 MP:0009286 increased abdominal fat pad weight "greater than average weight of the encapsulated adipose tissue in the abdomen" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pltptm2.1Jia/Pltptm2.1Jia
Genetic Background: involves: C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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