ENSMUSG00000051149


Mus musculus

Features
Gene ID: ENSMUSG00000051149
  
Biological name :Adnp
  
Synonyms : Activity-dependent neuroprotector homeobox protein / Adnp / Q9Z103
  
Possible biological names infered from orthology : activity dependent neuroprotector homeobox / Q9H2P0
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H3
Gene start: 168180986
Gene end: 168207112
  
Corresponding Affymetrix probe sets: 10489936 (MoGene1.0st)   1423069_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000056809
Ensembl peptide - ENSMUSP00000085316
NCBI entrez gene - 11538     See in Manteia.
MGI - MGI:1338758
RefSeq - NM_001310088
RefSeq - NM_001310086
RefSeq - NM_009628
RefSeq Peptide - NP_001297015
RefSeq Peptide - NP_001297017
RefSeq Peptide - NP_033758
swissprot - Q9Z103
Ensembl - ENSMUSG00000051149
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adnpaENSDARG00000062002Danio rerio
 adnpbENSDARG00000074293Danio rerio
 ADNPENSGALG00000007989Gallus gallus
 ADNPENSG00000101126Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Adnp2 / Q8CHC8 / Activity-dependent neuroprotector homeobox protein 2 / Q6IQ32* / ADNP homeobox 2*ENSMUSG0000005395024


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007614 short-term memory IEA
 biological_processGO:0009743 response to carbohydrate IEA
 biological_processGO:0010035 response to inorganic substance IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0010835 regulation of protein ADP-ribosylation IEA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0030828 obsolete positive regulation of cGMP biosynthetic process IEA
 biological_processGO:0031668 cellular response to extracellular stimulus IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0033484 nitric oxide homeostasis IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0044849 estrous cycle IEA
 biological_processGO:0045773 positive regulation of axon extension IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0050805 negative regulation of synaptic transmission IEA
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus IC
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042277 peptide binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048487 beta-tubulin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000928 incomplete cephalic closure "arrest of the fusion of the cephalic neural folds" [J:12622]
Show

Allelic Composition: Slc4a1l11Jus51/Slc4a1l11Jus51
Genetic Background: involves: C57BL/6J

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc4a1l11Jus51/Slc4a1l11Jus51
Genetic Background: involves: C57BL/6J

 MP:0011097 complete embryonic lethality before turning of embryo "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith]
Show

Allelic Composition: Slc4a1l11Jus51/Slc4a1l11Jus51
Genetic Background: involves: C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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