ENSMUSG00000051256


Mus musculus

Features
Gene ID: ENSMUSG00000051256
  
Biological name :Jagn1
  
Synonyms : 1 / Jagn1 / Q5XKN4
  
Possible biological names infered from orthology : jagunal homolog 1 / Q8N5M9
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: E3
Gene start: 113442569
Gene end: 113448229
  
Corresponding Affymetrix probe sets: 10540676 (MoGene1.0st)   1417064_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000098631
Ensembl peptide - ENSMUSP00000145000
NCBI entrez gene - 67767     See in Manteia.
MGI - MGI:1915017
RefSeq - NM_001243739
RefSeq - NM_026365
RefSeq Peptide - NP_001230668
RefSeq Peptide - NP_080641
swissprot - Q5XKN4
swissprot - A0A0N4SV89
Ensembl - ENSMUSG00000051256
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 jagn1aENSDARG00000041071Danio rerio
 jagn1bENSDARG00000014995Danio rerio
 JAGN1ENSGALG00000031797Gallus gallus
 JAGN1ENSG00000171135Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009787  Protein jagunal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002446 neutrophil mediated immunity IMP
 biological_processGO:0007029 endoplasmic reticulum organization IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0038158 granulocyte colony-stimulating factor signaling pathway IEA
 biological_processGO:0050832 defense response to fungus IMP
 biological_processGO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:1904577 cellular response to tunicamycin IEA
 biological_processGO:1990266 neutrophil migration IMP
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002463 abnormal neutrophil physiology "abnormal function of these granular leukocytes, which stain with neutral dyes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pepddal/Pepddal
Genetic Background: involves: CAST/EiJ * CBA/J

 MP:0005065 abnormal neutrophil morphology "structural anomaly of the granular leukocytes that have a three- to five-lobed nucleus and a cytoplasm that contains inconspicuous granules stainable by neutral dyes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pepddal/Pepddal
Genetic Background: involves: CAST/EiJ * CBA/J

 MP:0005399 increased susceptibility to fungal infection "greater likelihood that an organism will develop ill effects from infection by a yeast or mold, or from components of, or toxins produced by, these organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pepddal/Pepddal
Genetic Background: involves: CAST/EiJ * CBA/J

 MP:0008719 impaired neutrophil recruitment "reduced diffusion or accumulation of neutrophils in tissues or cells in response to a wide variety of substances released at the sites of inflammatory reactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pepddal/Pepddal
Genetic Background: involves: CAST/EiJ * CBA/J

 MP:0008720 impaired neutrophil migration "defect in the ability of neutrophils to move along a chemotactic gradient" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pepddal/Pepddal
Genetic Background: involves: CAST/EiJ * CBA/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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