ENSMUSG00000051343


Mus musculus

Features
Gene ID: ENSMUSG00000051343
  
Biological name :Rab11fip5
  
Synonyms : Q8R361 / Rab11 family-interacting protein 5 / Rab11fip5
  
Possible biological names infered from orthology : Q9BXF6
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: C3
Gene start: 85334962
Gene end: 85374634
  
Corresponding Affymetrix probe sets: 10545827 (MoGene1.0st)   1427405_s_at (Mouse Genome 430 2.0 Array)   1434314_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000058305
Ensembl peptide - ENSMUSP00000145402
NCBI entrez gene - 52055     See in Manteia.
MGI - MGI:1098586
RefSeq - XM_006506366
RefSeq - NM_001003955
RefSeq - NM_177466
RefSeq Peptide - NP_001003955
RefSeq Peptide - NP_803417
swissprot - Q8R361
swissprot - A0A0N4SW73
Ensembl - ENSMUSG00000051343
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01048053.1ENSDARG00000101188Danio rerio
 rab11fip5aENSDARG00000104179Danio rerio
 Q9BXF6ENSG00000135631Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9D620 / Rab11fip1 / Rab11 family-interacting protein 1 / Q6WKZ4*ENSMUSG0000003148821
G3XA57 / Rab11fip2 / RAB11 family interacting protein 2 (class I) / Q7L804* / RAB11 family interacting protein 2*ENSMUSG0000004002213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR019018  Rab-binding domain FIP-RBD
 IPR035892  C2 domain superfamily
 IPR037245  FIP-RBD, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0035773 insulin secretion involved in cellular response to glucose stimulus IMP
 biological_processGO:0045055 regulated exocytosis IMP
 biological_processGO:0070164 negative regulation of adiponectin secretion ISO
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 biological_processGO:0071468 cellular response to acidic pH ISO
 biological_processGO:2000008 regulation of protein localization to cell surface ISO
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005741 mitochondrial outer membrane ISO
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005815 microtubule organizing center ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030141 secretory granule IDA
 cellular_componentGO:0030658 transport vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 cellular_componentGO:0045335 phagocytic vesicle IDA
 cellular_componentGO:0055037 recycling endosome IDA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0017137 Rab GTPase binding IEA
 molecular_functionGO:0043015 gamma-tubulin binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptpn12tm1b(NCOM)Mfgc/Ptpn12tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc/Tcp

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Ptpn12tm1b(NCOM)Mfgc/Ptpn12tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc/Tcp

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Scn8aem1Mm/Scn8a+
Genetic Background: involves: C57BL/6J * SJL

 MP:0002965 hyperalbuminemia "blood albumin concentration above the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Ptpn12tm1b(NCOM)Mfgc/Ptpn12tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc/Tcp

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Ptpn12tm1b(NCOM)Mfgc/Ptpn12tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc/Tcp

 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Ptpn12tm1b(NCOM)Mfgc/Ptpn12tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc/Tcp

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptpn12tm1b(NCOM)Mfgc/Ptpn12tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc/Tcp

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Ptpn12tm1b(NCOM)Mfgc/Ptpn12tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc/Tcp

 MP:0011435 increased urine magnesium level "higher than normal amount of magnesium in the urine" [MGI:anna]
Show

Allelic Composition: Ptpn12tm1b(NCOM)Mfgc/Ptpn12tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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