ENSMUSG00000051483


Mus musculus

Features
Gene ID: ENSMUSG00000051483
  
Biological name :Cbr1
  
Synonyms : Carbonyl reductase [NADPH] 1 / Cbr1 / P48758
  
Possible biological names infered from orthology : carbonyl reductase 1 / P16152
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: C4
Gene start: 93607837
Gene end: 93610505
  
Corresponding Affymetrix probe sets: 10436967 (MoGene1.0st)   1460196_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000049394
NCBI entrez gene - 12408     See in Manteia.
MGI - MGI:88284
RefSeq - NM_007620
RefSeq Peptide - NP_031646
swissprot - B2RXY7
swissprot - P48758
Ensembl - ENSMUSG00000051483
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cbr1ENSDARG00000036587Danio rerio
 CBR1ENSGALG00000016027Gallus gallus
 CBR1ENSG00000159228Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm5678 / CBR1* / P16152* / carbonyl reductase 1*ENSMUSG0000008281587
Cbr3 / Q8K354 / Carbonyl reductase [NADPH] 3 / O75828* / carbonyl reductase 3*ENSMUSG0000002294775


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0017144 drug metabolic process ISO
 biological_processGO:0042373 vitamin K metabolic process ISO
 biological_processGO:0055114 oxidation-reduction process ISO
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004090 carbonyl reductase (NADPH) activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor ISO
 molecular_functionGO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity IEA
 molecular_functionGO:0050221 prostaglandin-E2 9-reductase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr