ENSMUSG00000051855


Mus musculus

Features
Gene ID: ENSMUSG00000051855
  
Biological name :Mest
  
Synonyms : Mesoderm-specific transcript protein / Mest / Q07646
  
Possible biological names infered from orthology : mesoderm specific transcript / Q5EB52
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: A3.3
Gene start: 30723547
Gene end: 30748465
  
Corresponding Affymetrix probe sets: 10537062 (MoGene1.0st)   1423294_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115541
Ensembl peptide - ENSMUSP00000145027
Ensembl peptide - ENSMUSP00000129639
Ensembl peptide - ENSMUSP00000120408
Ensembl peptide - ENSMUSP00000119038
Ensembl peptide - ENSMUSP00000117713
Ensembl peptide - ENSMUSP00000110780
NCBI entrez gene - 17294     See in Manteia.
MGI - MGI:96968
RefSeq - XM_017321427
RefSeq - NM_001252292
RefSeq - NM_001252293
RefSeq - NM_008590
RefSeq Peptide - NP_032616
RefSeq Peptide - NP_001239221
RefSeq Peptide - NP_001239222
swissprot - D3YZU2
swissprot - D3YZ83
swissprot - D3Z383
swissprot - A0A0N4SVB2
swissprot - Q07646
swissprot - D3Z3U2
Ensembl - ENSMUSG00000051855
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mestENSDARG00000032319Danio rerio
 MESTENSGALG00000008111Gallus gallus
 MESTENSG00000106484Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000073  Alpha/beta hydrolase fold-1
 IPR000639  Epoxide hydrolase-like
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010883 regulation of lipid storage IMP
 biological_processGO:0032526 response to retinoic acid IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H

 MP:0001384 abnormal pup retrieval "a mother does not retrieve stray pups to the nest or delays retrieving stray pups" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H

 MP:0001386 abnormal maternal nurturing "failure of mothers to tend offspring" [J:39801]
Show

Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H

Allelic Composition: Mesttm1Masu/Mest+
Genetic Background: involves: BALB/c

Allelic Composition: Mesttm1Masu/Mest+
Genetic Background: involves: C57BL/6 * CBA/Ca

 MP:0002189 abnormal myocardial trabeculae morphology "malformation of the supporting bundles of muscular fibers lining the walls of the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mesttm1Masu/Mest+
Genetic Background: involves: C57BL/6 * CBA/Ca

 MP:0003122 maternal imprinting "specific loci are inactivated during oogenesis and are not expressed in offspring" [llw2:Linda Washburn, Mouse Genome Informatics Curator, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H

Allelic Composition: Mesttm1Masu/Mest+
Genetic Background: involves: C57BL/6

Allelic Composition: Mesttm1Masu/Mest+
Genetic Background: involves: BALB/c

Allelic Composition: Mesttm1Masu/Mest+
Genetic Background: involves: C57BL/6 * CBA/Ca

Allelic Composition: Mesttm1Masu/Mest+
Genetic Background: Not Specified

 MP:0004200 reduced fetal size "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H

 MP:0004259 small placenta "reduced size of the size or shape of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H

 MP:0004921 decreased placenta weight "reduction in the weight of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H

 MP:0005329 abnormal cardiac muscle morphology "anomalous structure of the involuntary muscle comprising the myocardium " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mesttm1Masu/Mest+
Genetic Background: involves: C57BL/6 * CBA/Ca

 MP:0009431 decreased fetal weight "reduced weight of a fetus compared to controls (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
Show

Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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