| MP:0000005 | increased brown fat amount | "increased amount of thermogenic tissue in the body that is composed of cells containing multiple small fat droplets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:14208] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0000010 | abnormal abdominal fat pads | "malformed or aberrant size of the encapsulated adipose tissue in the abdomen" [J:65146] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0000445 | short snout | "reduced length of the anterior facial part of the muzzle" [J:53370] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0000598 | abnormal liver morphology | "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0000745 | tremors | "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0001258 | decreased body length | "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0001330 | abnormal optic nerve morphology | "malformation, misprojection or atrophy in the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0001429 | dehydration | "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0001492 | piloerection | "the involuntary bristling of hairs" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0001505 | hunched posture | "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0001783 | decreased white fat amount | "reduced quantity of fat-storing cells/tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0002090 | abnormal vision | "inability or decreased ability to see " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0002628 | fatty liver | "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0002753 | dilated left ventricle | "an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0002754 | dilated right ventricle | "an expansion in the volume of the lower right chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0002795 | dilated cardiomyopathy | "decreased function of the heart associated with cardiac enlargement and congestive heart failure" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0002970 | abnormal white fat morphology | "structural aberration in the connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0002971 | abnormal brown fat morphology | "defect in the thermogenic form of adipose tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0002981 | increased liver weight | "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0003662 | abnormal proliferative zone | "germinal layer of the epiphyseal plate where cells are actively dividing as well as producing extracellular matrix" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96254] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0003727 | abnormal retinal layer morphology | "malformation in any of the layers that make up the retina" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0003921 | abnormal left ventricle morphology | "structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0004701 | decreased circulating insulin-like growth factor I level | "reduced blood concentration of this polypeptide hormone with growth-regulating, insulin-like, and mitogenic activities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0004777 | abnormal phospholipid level | "anomalous concentration of the fat derivatives in which one fatty acid has been replaced by a phosphate group" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0005405 | axon degeneration | "retrogressive pathologic change in the single process of a nerve cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0005608 | cardiac interstitial fibrosis | "formation of fibrous tissue within the interstices of the heart as a result of repair or a reactive process" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0006035 | abnormal mitochondrial morphology | "anomalous structure of the mitochondria" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0006036 | abnormal mitochondrial physiology | |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0006303 | abnormal retinal nerve fiber layer morphology | "malformation of the layer of the retina formed by expansion of the fibers of the optic nerve" [ISBN:0-914294-08-3 "Gray s Anatomy", J:67382, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0006309 | decreased retinal ganglion cell number | "reduced number of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0006395 | abnormal epiphyseal plate morphology | "any structural anomaly of the cartilaginous center of ossification on the bones permitting growth of the bone in both directions during development" [MESH:A02.835.232.251.352] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0008507 | thin retinal ganglion layer | "reduced thickness of the innermost nuclear layer of the retina, which contains neurons that project axons through the optic nerve to the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0008513 | thin retinal inner plexiform layer | "reduced thickness of the retinal cell layer where bipolar and amacrine cell axons synapse with ganglion cell dendrites" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0008515 | thin retinal outer nuclear layer | "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0009269 | decreased fat cell size | "reduction in the size of fat-storing cells found mostly in the abdominal cavity and subcutaneous tissue of mammals" [CL:0000449] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0009355 | increased liver triglyceride level | "higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0009642 | abnormal blood homeostasis | "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0009703 | decreased birth body size | "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0010398 | decreased liver glycogen level | "less than the normal concentration of a readily converted carbohydrate reserve in liver" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0010499 | abnormal ventricle myocardium morphology | "any structural anomaly of the ventricular part of middle layer of the heart, comprised of involuntary muscle" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0010725 | thin interventricular septum | "decreased thickness of the wall between the two lower chambers of the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0011015 | decreased body surface temperature | "reduced degree of heat natural to skin-environment interface of a living being" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
| MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Mfrprd6/Mfrprd6
Genetic Background: involves: C3HfB6/Anl
|
