ENSMUSG00000052512


Mus musculus

Features
Gene ID: ENSMUSG00000052512
  
Biological name :Nav2
  
Synonyms : Nav2 / neuron navigator 2
  
Possible biological names infered from orthology : Q8IVL1
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B4
Gene start: 48908716
Gene end: 49610090
  
Corresponding Affymetrix probe sets: 10553354 (MoGene1.0st)   1430716_at (Mouse Genome 430 2.0 Array)   1435981_at (Mouse Genome 430 2.0 Array)   1441353_at (Mouse Genome 430 2.0 Array)   1442467_at (Mouse Genome 430 2.0 Array)   1444080_at (Mouse Genome 430 2.0 Array)   1444706_at (Mouse Genome 430 2.0 Array)   1444780_at (Mouse Genome 430 2.0 Array)   1457395_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138846
Ensembl peptide - ENSMUSP00000139309
Ensembl peptide - ENSMUSP00000139312
Ensembl peptide - ENSMUSP00000067448
Ensembl peptide - ENSMUSP00000139045
NCBI entrez gene - 78286     See in Manteia.
MGI - MGI:2183691
RefSeq - XM_017312397
RefSeq - NM_001111016
RefSeq - NM_175272
RefSeq - XM_006541306
RefSeq - XM_006541307
RefSeq - XM_006541308
RefSeq - XM_006541309
RefSeq - XM_006541310
RefSeq - XM_006541311
RefSeq - XM_017312396
RefSeq - XM_006541288
RefSeq - XM_006541289
RefSeq - XM_006541290
RefSeq - XM_006541291
RefSeq - XM_006541292
RefSeq - XM_006541293
RefSeq - XM_006541294
RefSeq - XM_006541295
RefSeq - XM_006541296
RefSeq - XM_006541297
RefSeq - XM_006541298
RefSeq - XM_006541299
RefSeq - XM_006541300
RefSeq - XM_006541302
RefSeq - XM_006541303
RefSeq - XM_006541304
RefSeq - XM_006541305
RefSeq Peptide - NP_001104486
RefSeq Peptide - NP_780481
swissprot - V9GWV3
swissprot - V9GX91
swissprot - V9GXT3
swissprot - V9GXT5
swissprot - E9Q842
Ensembl - ENSMUSG00000052512
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nav2aENSDARG00000073688Danio rerio
 nav2bENSDARG00000001879Danio rerio
 NAV2ENSGALG00000003999Gallus gallus
 NAV2ENSG00000166833Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nav3 / neuron navigator 3 / Q8IVL0*ENSMUSG0000002018155
Nav1 / Q8CH77 / Neuron navigator 1 / Q8NEY1*ENSMUSG0000000941832
B9EJA2 / Cttnbp2 / Cortactin-binding protein 2 / Q8WZ74*ENSMUSG0000000041612
Q99LJ0 / Cttnbp2nl / CTTNBP2 N-terminal-like protein / Q9P2B4* / CTTNBP2 N-terminal like*ENSMUSG000000621274


Protein motifs (from Interpro)
Interpro ID Name
 IPR001715  Calponin homology domain
 IPR003593  AAA+ ATPase domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback IMP
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007605 sensory perception of sound IMP
 biological_processGO:0007608 sensory perception of smell IMP
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0021554 optic nerve development IMP
 biological_processGO:0021563 glossopharyngeal nerve development IMP
 biological_processGO:0021564 vagus nerve development IMP
 cellular_componentGO:0005614 interstitial matrix IDA
 cellular_componentGO:0005654 nucleoplasm ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008201 heparin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
Show

Allelic Composition: Col19a1tm2Rmz/Col19a1tm2Rmz
Genetic Background: involves: 129T2/SvEmsJ

 MP:0001330 abnormal optic nerve morphology "malformation, misprojection or atrophy in the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col19a1tm2Rmz/Col19a1tm2Rmz
Genetic Background: involves: 129T2/SvEmsJ

 MP:0001417 decreased exploration in new environment "less amount of time spent investigating a new location" [J:79870]
Show

Allelic Composition: Col19a1tm2Rmz/Col19a1tm2Rmz
Genetic Background: involves: 129T2/SvEmsJ

 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
Show

Allelic Composition: Col19a1tm2Rmz/Col19a1tm2Rmz
Genetic Background: involves: 129T2/SvEmsJ

 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
Show

Allelic Composition: Col19a1tm2Rmz/Col19a1tm2Rmz
Genetic Background: involves: 129T2/SvEmsJ

 MP:0001984 abnormal olfaction "change in the ability to smell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Col19a1tm2Rmz/Col19a1tm2Rmz
Genetic Background: involves: 129T2/SvEmsJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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