ENSMUSG00000052656


Mus musculus

Features
Gene ID: ENSMUSG00000052656
  
Biological name :Rnf103
  
Synonyms : E3 ubiquitin-protein ligase RNF103 / Q9R1W3 / Rnf103
  
Possible biological names infered from orthology : O00237 / ring finger protein 103
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: C1
Gene start: 71493894
Gene end: 71510881
  
Corresponding Affymetrix probe sets: 10539002 (MoGene1.0st)   1443830_x_at (Mouse Genome 430 2.0 Array)   1448434_at (Mouse Genome 430 2.0 Array)   1458962_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000066324
Ensembl peptide - ENSMUSP00000109816
Ensembl peptide - ENSMUSP00000109817
NCBI entrez gene - 22644     See in Manteia.
MGI - MGI:109483
RefSeq - XM_006505926
RefSeq - NM_001308303
RefSeq - NM_009543
RefSeq Peptide - NP_001295232
RefSeq Peptide - NP_033569
swissprot - Q9R1W3
swissprot - D3Z0Y5
Ensembl - ENSMUSG00000052656
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf103ENSDARG00000100850Danio rerio
 RNF103ENSGALG00000015809Gallus gallus
 O00237ENSG00000239305Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination ISO
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Hsd11b1tm1.1Ggla/Hsd11b1tm1.1Ggla
Genetic Background: involves: 129P2/OlaHsd

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Hsd11b1tm1.1Ggla/Hsd11b1tm1.1Ggla
Genetic Background: involves: 129P2/OlaHsd

 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
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Allelic Composition: Hsd11b1tm1.1Ggla/Hsd11b1tm1.1Ggla
Genetic Background: involves: 129P2/OlaHsd

 MP:0009141 increased prepulse inhibition "increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Hsd11b1tm1.1Ggla/Hsd11b1tm1.1Ggla
Genetic Background: involves: 129P2/OlaHsd

 MP:0009453 enhanced contextual conditioning "increase in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and the neutral, unchanging environment (the conditioned stimulus (CS), or the environmental context in this case)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Hsd11b1tm1.1Ggla/Hsd11b1tm1.1Ggla
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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