Manteia - Molecule gene

ENSMUSG00000052852

Mus musculus

Features

Gene ID:	ENSMUSG00000052852

Biological name :	Reep1

Synonyms :	Q8BGH4 / Receptor expression-enhancing protein 1 / Reep1

Possible biological names infered from orthology :	Q9H902 / receptor accessory protein 1

Species:	Mus musculus

Chr. number:	6
Strand:	1
Band:	C1
Gene start:	71707561
Gene end:	71810710

Corresponding Affymetrix probe sets:	10539017 (MoGene1.0st) 1433509_s_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000112662 Ensembl peptide - ENSMUSP00000148678 Ensembl peptide - ENSMUSP00000148341 NCBI entrez gene - 52250 See in Manteia. MGI - MGI:1098827 RefSeq - NM_178608 RefSeq Peptide - NP_848723 swissprot - A0A1D5RM91 swissprot - A0A1D5RLF1 swissprot - Q8BGH4 Ensembl - ENSMUSG00000052852

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
reep1	ENSDARG00000014854	Danio rerio
REEP1	ENSGALG00000015786	Gallus gallus
REEP1	ENSG00000068615	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Reep2 / Q8VCD6 / Receptor expression-enhancing protein 2 / Q9BRK0* / receptor accessory protein 2*	ENSMUSG00000038555	68
Reep4 / Q8K072 / Receptor expression-enhancing protein 4 / Q9H6H4* / receptor accessory protein 4*	ENSMUSG00000033589	63
Reep3 / Q99KK1 / Receptor expression-enhancing protein 3 / Q6NUK4* / receptor accessory protein 3*	ENSMUSG00000019873	59
Reep5 / receptor accessory protein 5 / Q00765*	ENSMUSG00000005873	24
Reep6 / Q9JM62 / Receptor expression-enhancing protein 6 / Q96HR9* / receptor accessory protein 6*	ENSMUSG00000035504	23

Protein motifs (from Interpro)

Interpro ID	Name
IPR004345	TB2/DP1/HVA22-related protein

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0032386	regulation of intracellular transport	IDA
biological_process	GO:0051205	protein insertion into membrane	IEA
biological_process	GO:0071786	endoplasmic reticulum tubular network organization	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005739	mitochondrion	IEA
cellular_component	GO:0005783	endoplasmic reticulum	ISO
cellular_component	GO:0005789	endoplasmic reticulum membrane	IDA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0031966	mitochondrial membrane	IEA
cellular_component	GO:0071782	endoplasmic reticulum tubular network	IDA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0008017	microtubule binding	IEA
molecular_function	GO:0031849	olfactory receptor binding	IEA

Pathways (from Reactome)

Pathway description

Olfactory Signaling Pathway

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000160	kyphosis	"forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Col1a1^{tm1(tetO-cre)Haho}/?,Gfi1b^tm1.1Haho/Gfi1b^tm1.1Haho Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0000937	abnormal motor neuron morphology	"malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of motor impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]	Show Allelic Composition: Col1a1^{tm1(tetO-cre)Haho}/?,Gfi1b^tm1.1Haho/Gfi1b^tm1.1Haho Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 Allelic Composition: Reep1^tm1.1Cahb/Reep1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0001392	abnormal locomotor activity	"altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Col1a1^{tm1(tetO-cre)Haho}/?,Gfi1b^tm1.1Haho/Gfi1b^tm1.1Haho Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0001406	abnormal gait	"unusual or distinctive way of walking" [J:65038]	Show Allelic Composition: Col1a1^{tm1(tetO-cre)Haho}/?,Gfi1b^tm1.1Haho/Gfi1b^tm1.1Haho Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0001504	abnormal posture	"atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]	Show Allelic Composition: Col1a1^{tm1(tetO-cre)Haho}/?,Gfi1b^tm1.1Haho/Gfi1b^tm1.1Haho Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0005405	axon degeneration	"retrogressive pathologic change in the single process of a nerve cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Col1a1^{tm1(tetO-cre)Haho}/?,Gfi1b^tm1.1Haho/Gfi1b^tm1.1Haho Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr