ENSMUSG00000052934


Mus musculus

Features
Gene ID: ENSMUSG00000052934
  
Biological name :Fbxo31
  
Synonyms : F-box only protein 31 / Fbxo31 / Q3TQF0
  
Possible biological names infered from orthology : AC010531.1 / F-box protein 31 / Q5XUX0
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: E1
Gene start: 121549440
Gene end: 121578806
  
Corresponding Affymetrix probe sets: 10582229 (MoGene1.0st)   10582231 (MoGene1.0st)   1417969_at (Mouse Genome 430 2.0 Array)   1428926_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000057573
Ensembl peptide - ENSMUSP00000148763
NCBI entrez gene - 76454     See in Manteia.
MGI - MGI:1354708
RefSeq - XM_006531478
RefSeq - NM_133765
RefSeq - XM_006531477
RefSeq Peptide - NP_598526
swissprot - Q3TQF0
swissprot - A0A1D5RMG0
Ensembl - ENSMUSG00000052934
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxo31ENSDARG00000062195Danio rerio
 ENSGALG00000005779Gallus gallus
 AC010531.1ENSG00000131152Homo sapiens
 FBXO31ENSG00000103264Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR026941  F-box only protein 31
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0031145 anaphase-promoting complex-dependent catabolic process ISO
 biological_processGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0031571 mitotic G1 DNA damage checkpoint IEA
 biological_processGO:0050775 positive regulation of dendrite morphogenesis IEA
 biological_processGO:2001224 positive regulation of neuron migration IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IEA
 cellular_componentGO:0043025 neuronal cell body IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0030332 cyclin binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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