ENSMUSG00000054976


Mus musculus

Features
Gene ID: ENSMUSG00000054976
  
Biological name :Nyap2
  
Synonyms : neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2 / Nyap2
  
Possible biological names infered from orthology : neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 / Q9P242
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: C5
Gene start: 81076950
Gene end: 81341764
  
Corresponding Affymetrix probe sets: 10347781 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000122935
Ensembl peptide - ENSMUSP00000065468
Ensembl peptide - ENSMUSP00000109122
Ensembl peptide - ENSMUSP00000117661
Ensembl peptide - ENSMUSP00000120767
NCBI entrez gene - 241134     See in Manteia.
MGI - MGI:2443135
RefSeq - XM_017320661
RefSeq - NM_001356399
RefSeq - NM_001356400
RefSeq - NM_172849
RefSeq - XM_006496485
RefSeq - XM_006496486
RefSeq - XM_006496487
RefSeq - XM_006496488
RefSeq - XM_006496489
RefSeq - XM_006496490
RefSeq - NM_001356397
RefSeq Peptide - NP_001343327
RefSeq Peptide - NP_001343328
RefSeq Peptide - NP_001343329
RefSeq Peptide - NP_766437
RefSeq Peptide - NP_001343326
swissprot - A0A0R4J1X0
swissprot - A0A0R4J1I8
swissprot - D3Z3N9
swissprot - A0A0R4J0T9
Ensembl - ENSMUSG00000054976
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nyap2aENSDARG00000079581Danio rerio
 nyap2bENSDARG00000093357Danio rerio
 NYAP2ENSGALG00000004966Gallus gallus
 NYAP2ENSG00000144460Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nyap1 / Q6PFX7 / Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 / Q6ZVC0* / neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1*ENSMUSG0000004534828


Protein motifs (from Interpro)
Interpro ID Name
 IPR026722  Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1/2
 IPR026723  Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2
 IPR029353  Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0048812 neuron projection morphogenesis IEA
 cellular_componentGO:0005622 intracellular IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
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Allelic Composition: Gzmbtm1Ley/Gzmbtm1Ley,Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J

 MP:0002175 low brain weight "lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gzmbtm1Ley/Gzmbtm1Ley,Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J

 MP:0008415 abnormal neurite morphology "any structural anomaly of a neuronal process, either a dendrite or an axon in vivo, or a filamentous projection from a neuron such as is seen in tissue culture" [PMID:12951572]
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Allelic Composition: Gzmbtm1Ley/Gzmbtm1Ley,Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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