ENSMUSG00000055239


Mus musculus

Features
Gene ID: ENSMUSG00000055239
  
Biological name :Kcmf1
  
Synonyms : E3 ubiquitin-protein ligase KCMF1 / Kcmf1 / Q80UY2
  
Possible biological names infered from orthology : potassium channel modulatory factor 1 / Q9P0J7
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: C1
Gene start: 72841114
Gene end: 72899979
  
Corresponding Affymetrix probe sets: 10545471 (MoGene1.0st)   1418694_at (Mouse Genome 430 2.0 Array)   1418695_a_at (Mouse Genome 430 2.0 Array)   1449180_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000064410
Ensembl peptide - ENSMUSP00000145559
Ensembl peptide - ENSMUSP00000144910
Ensembl peptide - ENSMUSP00000144907
NCBI entrez gene - 74287     See in Manteia.
MGI - MGI:1921537
RefSeq - XM_017321793
RefSeq - NM_019715
RefSeq Peptide - NP_001334160
RefSeq Peptide - NP_062689
swissprot - A0A0N4SV15
swissprot - A0A0U1RNG8
swissprot - Q80UY2
swissprot - A0A0N4SV12
Ensembl - ENSMUSG00000055239
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcmf1ENSDARG00000067656Danio rerio
 ENSGALG00000015391Gallus gallus
 ENSGALG00000035780Gallus gallus
 KCMF1ENSG00000176407Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000433  Zinc finger, ZZ-type
 IPR008598  Drought induced 19 protein type, zinc-binding domain
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination ISO
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity ISO


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001944 abnormal pancreas morphology "malformation of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [il:Ira Lu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Krastm4Tyj/Krastm4Tyj,Ptf1atm1(cre)Hnak/Ptf1a+
Genetic Background: involves: 129S4/SvJae

 MP:0002052 decreased tumor incidence "less than the expected number of abnormal growths in a specific population" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Krastm4Tyj/Krastm4Tyj,Ptf1atm1(cre)Hnak/Ptf1a+
Genetic Background: involves: 129S4/SvJae

 MP:0002693 abnormal pancreas physiology "abberrant function of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Krastm4Tyj/Krastm4Tyj,Ptf1atm1(cre)Hnak/Ptf1a+
Genetic Background: involves: 129S4/SvJae

 MP:0008770 decreased survivor rate "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Zdhhc13skc4/Zdhhc13skc4
Genetic Background: involves: 129S6/SvEvTac * C3H * C57BL/6

 MP:0009109 decreased pancreas weight "reduction in the average weight of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [MESH:A03.734, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krastm4Tyj/Krastm4Tyj,Ptf1atm1(cre)Hnak/Ptf1a+
Genetic Background: involves: 129S4/SvJae

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Zdhhc13skc4/Zdhhc13skc4
Genetic Background: involves: 129S6/SvEvTac * C3H * C57BL/6

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
Show

Allelic Composition: Zdhhc13skc4/Zdhhc13skc4
Genetic Background: involves: 129S6/SvEvTac * C3H * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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