ENSMUSG00000056666


Mus musculus

Features
Gene ID: ENSMUSG00000056666
  
Biological name :Retsat
  
Synonyms : All-trans-retinol 13,14-reductase / Q64FW2 / Retsat
  
Possible biological names infered from orthology : Q6NUM9 / retinol saturase
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: C1
Gene start: 72598475
Gene end: 72608425
  
Corresponding Affymetrix probe sets: 10539143 (MoGene1.0st)   1424715_at (Mouse Genome 430 2.0 Array)   1424716_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000134847
Ensembl peptide - ENSMUSP00000135421
Ensembl peptide - ENSMUSP00000146069
Ensembl peptide - ENSMUSP00000068568
Ensembl peptide - ENSMUSP00000116567
NCBI entrez gene - 67442     See in Manteia.
MGI - MGI:1914692
RefSeq - NM_026159
RefSeq Peptide - NP_080435
swissprot - Q64FW2
swissprot - A0A0U1RPP6
swissprot - F7CW61
swissprot - H3BJ51
swissprot - H3BKK1
Ensembl - ENSMUSG00000056666
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5BLE8ENSDARG00000018600Danio rerio
 RETSATENSDARG00000070140Danio rerio
 Q6NUM9ENSG00000042445Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042572 retinol metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IDA
 cellular_componentGO:0005640 nuclear outer membrane IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 molecular_functionGO:0016491 oxidoreductase activity IDA
 molecular_functionGO:0051786 all-trans-retinol 13,14-reductase activity TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000010 abnormal abdominal fat pads "malformed or aberrant size of the encapsulated adipose tissue in the abdomen" [J:65146]
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Allelic Composition: Dixdc1tm1Bnrc/Dixdc1tm1Bnrc
Genetic Background: involves: 129 * C57BL/6

 MP:0005336 abnormal inguinal fat pad "malformed or aberrant size of the encapsulated adipose tissue found in the groin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:84541]
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Allelic Composition: Dixdc1tm1Bnrc/Dixdc1tm1Bnrc
Genetic Background: involves: 129 * C57BL/6

 MP:0005458 increased percent body fat "more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Dixdc1tm1Bnrc/Dixdc1tm1Bnrc
Genetic Background: involves: 129 * C57BL/6

 MP:0005561 increased mean corpuscular hemoglobin "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ptpn12tm1b(NCOM)Mfgc/Ptpn12tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc/Tcp

 MP:0005564 increased hemoglobin content "increase in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
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Allelic Composition: Ptpn12tm1b(NCOM)Mfgc/Ptpn12tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc/Tcp

 MP:0011167 abnormal adipose tissue development "anomaly in the process of the formation of the connective tissue composed of fat cells enmeshed in areolar tissue" [MESH:A10.165.114, MGI:csmith]
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Allelic Composition: Dixdc1tm1Bnrc/Dixdc1tm1Bnrc
Genetic Background: involves: 129 * C57BL/6

 MP:0011233 abnormal vitamin A metabolism "altered ability to metabolize any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid; animals can not synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids supplied in the diet" [GO:0035238]
Show

Allelic Composition: Dixdc1tm1Bnrc/Dixdc1tm1Bnrc
Genetic Background: involves: 129 * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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