ENSMUSG00000056947


Mus musculus

Features
Gene ID: ENSMUSG00000056947
  
Biological name :Mab21l1
  
Synonyms : Mab21l1 / O70299 / Putative nucleotidyltransferase MAB21L1
  
Possible biological names infered from orthology : mab-21 like 1 / Q13394
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: C
Gene start: 55782510
Gene end: 55785001
  
Corresponding Affymetrix probe sets: 10492169 (MoGene1.0st)   1421369_a_at (Mouse Genome 430 2.0 Array)   1424679_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000074878
NCBI entrez gene - 17116     See in Manteia.
MGI - MGI:1333773
RefSeq - NM_010750
RefSeq Peptide - NP_034880
swissprot - O70299
Ensembl - ENSMUSG00000056947
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6NYB4ENSDARG00000102047Danio rerio
 Q8AY65ENSGALG00000045052Gallus gallus
 Q13394ENSG00000180660Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BPP1 / Mab21l2 / Protein mab-21-like 2 / Q9Y586* / mab-21 like 2*ENSMUSG0000005777794
Q8CI17 / Mab21l3 / Protein mab-21-like 3 / Q8N8X9* / mab-21 like 3*ENSMUSG0000004431324
Q8CEZ4 / 2310007B03Rik / Uncharacterized / Q08AI8* / C2orf54* / chromosome 2 open reading frame 54*ENSMUSG0000003415917


Protein motifs (from Interpro)
Interpro ID Name
 IPR024810  Mab-21 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0043010 camera-type eye development IMP
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0001312 abnormal cornea morphology "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0002716 small preputial glands "reduced size of the sebaceous glands of the corona and neck of the glans penis" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, il:Ira Lu , Mouse Genome Informatics Curator, J:82312]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0002717 abnormal preputial gland morphology "anomalous structure of the sebaceous glands of the corona and neck of the glans penis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0003078 aphakia "absence of the crystalline lens of the eye" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0005193 abnormal anterior eye segment morphology "anomalous structure of any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0005201 abnormal retinal pigment epithelium morphology "anomaly in the epithelial layer of the retina composed of cells containing pigment granules " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0005261 aniridia "abnormality in which there is only a rudimentary iris, due to the failure of optic cup growth" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0008511 thin retinal inner nuclear layer "reduced thickness of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0008515 thin retinal outer nuclear layer "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0009725 absent lens vesicle "absence of the ectodermal invagination that forms opposite the optic cup in the primordium of the lens of the eye" [ISBN:0-12-402035-6 "Kaufman, MH The Atlas of Mouse Development", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0011962 increased cornea thickness "increased width of the cornea in the center plane" [MGI:csmith]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0011964 increased total retina thickness "increased width of the retina through the center plane" [MGI:csmith]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0012168 abnormal optic placode morphology "any structural anomaly of the paired thickenings of surface ectoderm that become invaginated to form the embryonic lens vesicles" [MGI:anna]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

 MP:0013742 absent ciliary body "absence of the thickened portion of the vascular tunic, which lies between the choroid and the iris" [ISBN:0-683-40008-8, MGI:Anna]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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