ENSMUSG00000057454


Mus musculus

Features
Gene ID: ENSMUSG00000057454
  
Biological name :Lypd3
  
Synonyms : Ly6/PLAUR domain-containing protein 3 / Lypd3 / Q91YK8
  
Possible biological names infered from orthology : LY6/PLAUR domain containing 3 / O95274
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: A3
Gene start: 24636550
Gene end: 24641118
  
Corresponding Affymetrix probe sets: 10550980 (MoGene1.0st)   1417942_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000079543
NCBI entrez gene - 72434     See in Manteia.
MGI - MGI:1919684
RefSeq - NM_133743
RefSeq Peptide - NP_598504
swissprot - Q91YK8
Ensembl - ENSMUSG00000057454
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LYPD3ENSG00000124466Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lypd5 / Q9D7Z7 / Ly6/PLAUR domain-containing protein 5 / Q6UWN5* / LY6/PLAUR domain containing 5*ENSMUSG0000003048418


Protein motifs (from Interpro)
Interpro ID Name
 IPR016054  Ly-6 antigen/uPA receptor-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007160 cell-matrix adhesion IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0043236 laminin binding IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000195 hypocalcemia "subnormal concentrations of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ltatm1.1(KOMP)Vlcg/Ltatm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ltatm1.1(KOMP)Vlcg/Ucd

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Ica1tm1Mdos/Ica1tm1Mdos,Ica1lem1Jxia/Ica1lem1Jxia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0001552 increased circulating triglyceride level "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]
Show

Allelic Composition: Ltatm1.1(KOMP)Vlcg/Ltatm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ltatm1.1(KOMP)Vlcg/Ucd

 MP:0002908 delayed wound healing "longer time requirement for the ability to self-repair and close wounds than normal" [J:63037]
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Allelic Composition: Ica1tm1Mdos/Ica1tm1Mdos,Ica1lem1Jxia/Ica1lem1Jxia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0002966 decreased circulating alkaline phosphatase level "reduced activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ltatm1.1(KOMP)Vlcg/Ltatm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ltatm1.1(KOMP)Vlcg/Ucd

 MP:0004502 decreased incidence of chemically-induced tumors "lower than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ica1tm1Mdos/Ica1tm1Mdos,Ica1lem1Jxia/Ica1lem1Jxia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0005012 decreased eosinophil count "fewer than normal eosinophil numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ltatm1.1(KOMP)Vlcg/Ltatm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ltatm1.1(KOMP)Vlcg/Ucd

 MP:0005459 decreased percent body fat "less fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ica1tm1Mdos/Ica1tm1Mdos,Ica1lem1Jxia/Ica1lem1Jxia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0005633 increased circulating sodium level "greater than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Ltatm1.1(KOMP)Vlcg/Ltatm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ltatm1.1(KOMP)Vlcg/Ucd

 MP:0008844 decreased subcutaneous adipose tissue amount "reduction in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ica1tm1Mdos/Ica1tm1Mdos,Ica1lem1Jxia/Ica1lem1Jxia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0008853 decreased abdominal adipose tissue amount "reduction in amount of adipose tissue associated with internal organs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ica1tm1Mdos/Ica1tm1Mdos,Ica1lem1Jxia/Ica1lem1Jxia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Jam3tm1.1(KOMP)Vlcg/Jam3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Jam3tm1.1(KOMP)Vlcg/J

 MP:0011940 decreased food intake "reduction in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]
Show

Allelic Composition: Ica1tm1Mdos/Ica1tm1Mdos,Ica1lem1Jxia/Ica1lem1Jxia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0014143 decreased body fat mass "decreased physical bulk or volume of fat in the whole body" [MGI:csmith]
Show

Allelic Composition: Ica1tm1Mdos/Ica1tm1Mdos,Ica1lem1Jxia/Ica1lem1Jxia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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