ENSMUSG00000058793


Mus musculus

Features
Gene ID: ENSMUSG00000058793
  
Biological name :Cds2
  
Synonyms : Cds2 / Phosphatidate cytidylyltransferase 2 / Q99L43
  
Possible biological names infered from orthology : CDP-diacylglycerol synthase 2 / O95674
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: F2
Gene start: 132263148
Gene end: 132312050
  
Corresponding Affymetrix probe sets: 10476326 (MoGene1.0st)   1418794_at (Mouse Genome 430 2.0 Array)   1418795_at (Mouse Genome 430 2.0 Array)   1434256_s_at (Mouse Genome 430 2.0 Array)   1438957_x_at (Mouse Genome 430 2.0 Array)   1452832_s_at (Mouse Genome 430 2.0 Array)   1454891_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135710
Ensembl peptide - ENSMUSP00000135497
Ensembl peptide - ENSMUSP00000086886
Ensembl peptide - ENSMUSP00000105786
Ensembl peptide - ENSMUSP00000099470
Ensembl peptide - ENSMUSP00000121769
NCBI entrez gene - 110911     See in Manteia.
MGI - MGI:1332236
RefSeq - NM_001291040
RefSeq - NM_001291039
RefSeq - NM_138651
RefSeq Peptide - NP_001277968
RefSeq Peptide - NP_619592
RefSeq Peptide - NP_001277969
swissprot - Q99L43
swissprot - A2AMQ5
swissprot - F6S4G2
swissprot - H3BKR7
swissprot - H3BLA1
swissprot - Q6PBC0
Ensembl - ENSMUSG00000058793
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cds2ENSDARG00000035577Danio rerio
 CDS2ENSGALG00000030406Gallus gallus
 CDS2ENSG00000101290Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cds1 / P98191 / Phosphatidate cytidylyltransferase 1 / Q92903* / CDP-diacylglycerol synthase 1*ENSMUSG0000002933072


Protein motifs (from Interpro)
Interpro ID Name
 IPR000374  Phosphatidate cytidylyltransferase
 IPR016720  Phosphatidate cytidylyltransferase, eukaryota


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006655 phosphatidylglycerol biosynthetic process IBA
 biological_processGO:0007602 phototransduction TAS
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0016024 CDP-diacylglycerol biosynthetic process IEA
 biological_processGO:0070085 glycosylation NAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum NAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004605 phosphatidate cytidylyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016772 transferase activity, transferring phosphorus-containing groups IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PG


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Cd28tm1a(EUCOMM)Hmgu/Cd28tm1a(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Cd28tm1a(EUCOMM)Hmgu/H

 MP:0003889 enhanced sensorimotor gating 
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Allelic Composition: Atp1a1Gt(OST31117)Lex/Atp1a1Gt(OST31117)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0005015 increased T cell number "greater than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Atp1a1Gt(OST31117)Lex/Atp1a1Gt(OST31117)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0005017 decreased B cell number "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Atp1a1Gt(OST31117)Lex/Atp1a1Gt(OST31117)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Atp1a1Gt(OST31117)Lex/Atp1a1Gt(OST31117)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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