ENSMUSG00000060240


Mus musculus

Features
Gene ID: ENSMUSG00000060240
  
Biological name :Cend1
  
Synonyms : Cell cycle exit and neuronal differentiation protein 1 / Cend1 / Q9JKC6
  
Possible biological names infered from orthology : cell cycle exit and neuronal differentiation 1 / Q8N111
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F5
Gene start: 141426446
Gene end: 141429491
  
Corresponding Affymetrix probe sets: 10569163 (MoGene1.0st)   1421348_a_at (Mouse Genome 430 2.0 Array)   1421349_x_at (Mouse Genome 430 2.0 Array)   1424100_s_at (Mouse Genome 430 2.0 Array)   1451235_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000081476
Ensembl peptide - ENSMUSP00000118591
Ensembl peptide - ENSMUSP00000123334
Ensembl peptide - ENSMUSP00000131085
NCBI entrez gene - 57754     See in Manteia.
MGI - MGI:1929898
RefSeq - NM_021316
RefSeq - XM_006536217
RefSeq Peptide - NP_067291
swissprot - Q9JKC6
Ensembl - ENSMUSG00000060240
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CEND1ENSG00000184524Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR020162  Cell cycle exit/neuronal differentiation protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007628 adult walking behavior IMP
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0021686 cerebellar granular layer maturation IMP
 biological_processGO:0021702 cerebellar Purkinje cell differentiation IMP
 biological_processGO:0021933 radial glia guided migration of cerebellar granule cell IMP
 biological_processGO:0021941 negative regulation of cerebellar granule cell precursor proliferation IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030182 neuron differentiation IMP
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031982 vesicle ISO
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000872 abnormal external granule cell layer "malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0000890 thin cerebellar molecular layer "reduced width of the outer of the three cortical layers of the cerebellum" [J:46854]
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Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0008572 abnormal Purkinje cell dendrite morphology "any strucutral anomaly of the Purkinje cell body projections with hundreds of parallel spiny branches reaching up into the molecular layer" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0009967 abnormal neuron proliferation "any anomaly in the ability of a neuron to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0009977 abnormal cerebellar granule cell migration "defective or impaired movement of cerebellar granule cell neurons from the germinal zone into the granule cell layer of the cerebellum during development of the cerebellar cortex" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0010540 long stride length "increased average distance between steps" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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