ENSMUSG00000060657


Mus musculus

Features
Gene ID: ENSMUSG00000060657
  
Biological name :Marf1
  
Synonyms : Marf1 / Meiosis regulator and mRNA stability factor 1 / Q8BJ34
  
Possible biological names infered from orthology : Q9Y4F3
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: A1
Gene start: 14109173
Gene end: 14163351
  
Corresponding Affymetrix probe sets: 10437852 (MoGene1.0st)   1445862_at (Mouse Genome 430 2.0 Array)   1455381_at (Mouse Genome 430 2.0 Array)   1459879_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000087770
Ensembl peptide - ENSMUSP00000154869
NCBI entrez gene - 223989     See in Manteia.
MGI - MGI:2444505
RefSeq - XM_006522019
RefSeq - NM_001081154
RefSeq - XM_006522018
RefSeq Peptide - NP_001074623
swissprot - Q8BJ34
Ensembl - ENSMUSG00000060657
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CZQB01141835.2ENSDARG00000115222Danio rerio
 MARF1ENSGALG00000039815Gallus gallus
 MARF1ENSG00000166783Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR021139  NYN domain, limkain-b1-type
 IPR024582  Marf1, conserved domain
 IPR024768  Meiosis regulator and mRNA stability factor 1
 IPR025605  OST-HTH/LOTUS domain
 IPR029060  PIN-like domain superfamily
 IPR034189  Marf1, RNA recognition motif 1
 IPR034191  Marf1, RNA recognition motif 2
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0007143 female meiotic nuclear division IMP
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010923 negative regulation of phosphatase activity IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0048477 oogenesis IMP
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Dll1tm1.1Hri/Dll1tm1.1Hri,Foxa2tm3.1(icre)Heli/Foxa2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

Allelic Composition: Marf1Gt(AS0671)Wtsi/Marf1m1Rpg
Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J

Allelic Composition: Marf1m1Rpg/Marf1m1Rpg
Genetic Background: B6;C3Fe-Marf1m1Rpg/J

 MP:0010767 abnormal female meiosis I arrest "any anomaly in the process in which oocytes stop at the diplotene stage of meiosis I and lie dormant, often for long periods of time" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Marf1m1Rpg/Marf1m1Rpg
Genetic Background: B6;C3Fe-Marf1m1Rpg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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