ENSMUSG00000061082


Mus musculus

Features
Gene ID: ENSMUSG00000061082
  
Biological name :Plac1
  
Synonyms : Mus musculus placental specific protein 1 (Plac1), transcript variant 2, mRNA. / Plac1 / Q9JI83
  
Possible biological names infered from orthology : placenta specific 1 / Q9HBJ0
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A5
Gene start: 53069995
Gene end: 53240111
  
Corresponding Affymetrix probe sets: 10604616 (MoGene1.0st)   1417553_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000074404
Ensembl peptide - ENSMUSP00000110492
Ensembl peptide - ENSMUSP00000133862
NCBI entrez gene - 56096     See in Manteia.
MGI - MGI:1926287
RefSeq - XM_011251016
RefSeq - NM_001357802
RefSeq - NM_019538
RefSeq - XM_006541524
RefSeq - XM_006541525
RefSeq Peptide - NP_001344731
RefSeq Peptide - NP_062411
swissprot - Q9JI83
Ensembl - ENSMUSG00000061082
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLAC1ENSG00000170965Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Oosp2 / Q4FZG8 / Oocyte-secreted protein 2 / Q86WS3*ENSMUSG0000005589524


Protein motifs (from Interpro)
Interpro ID Name
 IPR033220  Placenta-specific protein 1
 IPR033222  PLAC1 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001890 placenta development IEP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0090214 spongiotrophoblast layer developmental growth IMP
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005576 extracellular region IDA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Plac1tm1(KOMP)Vlcg/Plac1+
Genetic Background: C57BL/6N-Plac1tm1(KOMP)Vlcg

 MP:0001712 abnormal placental development "malformed or incomplete differentiation of the organ of metabolic exchange between the fetus and mother" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]
Show

Allelic Composition: Chn2tm2.1Alk/Chn2+,Nrp2Gt(GST039)Byg/Nrp2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * FVB/N

Allelic Composition: Plac1tm1(KOMP)Vlcg/Plac1+
Genetic Background: C57BL/6N-Plac1tm1(KOMP)Vlcg

 MP:0003123 paternal imprinting "specific loci are inactivated during spermatogenesis and are not expressed in offspring " [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator, llw2:Linda Washburn, Mouse Genome Informatics Curator]
Show

Allelic Composition: Plac1tm1(KOMP)Vlcg/Plac1+
Genetic Background: C57BL/6N-Plac1tm1(KOMP)Vlcg

 MP:0004260 enlarged placenta "increased size of the size or shape of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Plac1tm1(KOMP)Vlcg/Plac1+
Genetic Background: C57BL/6N-Plac1tm1(KOMP)Vlcg

 MP:0004920 increased placenta weight "increase in the weight of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Chn2tm2.1Alk/Chn2+,Nrp2Gt(GST039)Byg/Nrp2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * FVB/N

Allelic Composition: Plac1tm1(KOMP)Vlcg/Plac1+
Genetic Background: C57BL/6N-Plac1tm1(KOMP)Vlcg

 MP:0008957 abnormal placenta junctional zone morphology "fetally derived placental region that separates the maternal uterine tissue from the placenta labyrinth" [PMID:16367805]
Show

Allelic Composition: Plac1tm1(KOMP)Vlcg/Plac1+
Genetic Background: C57BL/6N-Plac1tm1(KOMP)Vlcg

 MP:0009397 increased trophoblast giant cell number "greater than normal number of cells of the extraembryonic cell layer that contributes to the placenta" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Chn2tm2.1Alk/Chn2+,Nrp2Gt(GST039)Byg/Nrp2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * FVB/N

Allelic Composition: Plac1tm1(KOMP)Vlcg/Plac1+
Genetic Background: C57BL/6N-Plac1tm1(KOMP)Vlcg

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Chn2tm2.1Alk/Chn2+,Nrp2Gt(GST039)Byg/Nrp2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * FVB/N

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Plac1tm1(KOMP)Vlcg/Plac1+
Genetic Background: C57BL/6N-Plac1tm1(KOMP)Vlcg

 MP:0012098 increased spongiotrophoblast size "greater size of the middle layer of the placenta between the outermost giant cells and the innermost labyrinth layer; it has a structural role and also produces several layer-specific secreted factors" [MGI:csmith]
Show

Allelic Composition: Chn2tm2.1Alk/Chn2+,Nrp2Gt(GST039)Byg/Nrp2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * FVB/N

Allelic Composition: Plac1tm1(KOMP)Vlcg/Plac1+
Genetic Background: C57BL/6N-Plac1tm1(KOMP)Vlcg

Allelic Composition: Plac1tm1(KOMP)Vlcg/Y
Genetic Background: C57BL/6N-Plac1tm1(KOMP)Vlcg

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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