ENSMUSG00000062190


Mus musculus

Features
Gene ID: ENSMUSG00000062190
  
Biological name :Lancl2
  
Synonyms : Lancl2 / LanC-like protein 2 / Q9JJK2
  
Possible biological names infered from orthology : LanC like 2 / Q9NS86
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: B3
Gene start: 57702540
Gene end: 57739439
  
Corresponding Affymetrix probe sets: 10538617 (MoGene1.0st)   1420856_a_at (Mouse Genome 430 2.0 Array)   1420857_at (Mouse Genome 430 2.0 Array)   1450028_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121377
Ensembl peptide - ENSMUSP00000072723
Ensembl peptide - ENSMUSP00000052146
NCBI entrez gene - 71835     See in Manteia.
MGI - MGI:1919085
RefSeq - NM_133737
RefSeq Peptide - NP_598498
swissprot - Q9JJK2
swissprot - F6RJV6
Ensembl - ENSMUSG00000062190
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lancl2ENSDARG00000045465Danio rerio
 LANCL2ENSGALG00000032570Gallus gallus
 LANCL2ENSG00000132434Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lancl1 / O89112 / LanC-like protein 1 / O43813* / LanC like 1*ENSMUSG0000002600051
Lancl3 / Q8CD19 / LanC-like protein 3 / Q6ZV70* / LanC like 3*ENSMUSG0000004734430


Protein motifs (from Interpro)
Interpro ID Name
 IPR007822  Lanthionine synthetase C-like
 IPR020464  LanC-like protein, eukaryotic


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0009789 positive regulation of abscisic acid-activated signaling pathway IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0010314 phosphatidylinositol-5-phosphate binding IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:0070273 phosphatidylinositol-4-phosphate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Krit1tm1.1(KOMP)Vlcg/Krit1+
Genetic Background: C57BL/6N-Krit1tm1.1(KOMP)Vlcg/Ucd

 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
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Allelic Composition: Krit1tm1.1(KOMP)Vlcg/Krit1+
Genetic Background: C57BL/6N-Krit1tm1.1(KOMP)Vlcg/Ucd

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Krit1tm1.1(KOMP)Vlcg/Krit1+
Genetic Background: C57BL/6N-Krit1tm1.1(KOMP)Vlcg/Ucd

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Rp2Gt(EUCJ0183f04)Hmgu/Rp2Gt(EUCJ0183f04)Hmgu
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0003068 enlarged kidney "larger than average size of the kidney" [J:86005, pvb:Pierre Vanden Borre, Mouse Genome Informatics Curator]
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Allelic Composition: Krit1tm1.1(KOMP)Vlcg/Krit1+
Genetic Background: C57BL/6N-Krit1tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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