ENSMUSG00000062202


Mus musculus

Features
Gene ID: ENSMUSG00000062202
  
Biological name :Btbd9
  
Synonyms : Btbd9 / BTB/POZ domain-containing protein 9 / Q8C726
  
Possible biological names infered from orthology : BTB domain containing 9 / Q96Q07
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A3.3
Gene start: 30215524
Gene end: 30576287
  
Corresponding Affymetrix probe sets: 10449631 (MoGene1.0st)   1431230_a_at (Mouse Genome 430 2.0 Array)   1434769_at (Mouse Genome 430 2.0 Array)   1435706_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000078845
Ensembl peptide - ENSMUSP00000127300
NCBI entrez gene - 224671     See in Manteia.
MGI - MGI:1916625
RefSeq - XM_011246395
RefSeq - NM_027060
RefSeq - NM_172618
RefSeq - XM_006524094
RefSeq Peptide - NP_081336
RefSeq Peptide - NP_766206
swissprot - Q8C726
Ensembl - ENSMUSG00000062202
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 btbd9ENSDARG00000068983Danio rerio
 BTBD9ENSGALG00000010131Gallus gallus
 BTBD9ENSG00000183826Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Btbd6 / Q8K2J9 / BTB/POZ domain-containing protein 6 / Q96KE9* / BTB domain containing 6*ENSMUSG0000000280318
Btbd3 / P58545 / BTB/POZ domain-containing protein 3 / Q9Y2F9* / BTB domain containing 3*ENSMUSG0000006209818
Btbd2 / BTB (POZ) domain containing 2 / Q9BX70* / BTB domain containing 2*ENSMUSG0000000334417
Btbd1 / P58544 / BTB/POZ domain-containing protein 1 / Q9H0C5* / BTB domain containing 1*ENSMUSG0000002510316
Btbd19 / BTB (POZ) domain containing 19 / C9JJ37* / BTB domain containing 19*ENSMUSG0000007377112


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR000421  Coagulation factor 5/8 C-terminal domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR034091  BTBD9, BACK-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007616 long-term memory IMP
 biological_processGO:0008344 adult locomotory behavior IMP
 biological_processGO:0030162 regulation of proteolysis IBA
 biological_processGO:0042428 serotonin metabolic process IMP
 biological_processGO:0042748 circadian sleep/wake cycle, non-REM sleep IMP
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0048512 circadian behavior IMP
 biological_processGO:0050804 modulation of chemical synaptic transmission IBA
 biological_processGO:0050951 sensory perception of temperature stimulus IMP
 biological_processGO:0060586 multicellular organismal iron ion homeostasis IMP
 biological_processGO:1900242 regulation of synaptic vesicle endocytosis IMP
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

 MP:0001396 unidirectional circling "circling behavior in one direction only, either clockwise or counterclockwise" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Usp9xtm1Tuv/Usp9x+
Genetic Background: involves: 129S4/SvJae * FVB/N

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Usp9xtm1Tuv/Usp9x+
Genetic Background: involves: 129S4/SvJae * FVB/N

 MP:0001501 abnormal sleep pattern "deviation from the normal wake/sleep cycle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Usp9xtm1Tuv/Usp9x+
Genetic Background: involves: 129S4/SvJae * FVB/N

 MP:0001556 increased circulating HDL cholesterol level "higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439]
Show

Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

 MP:0003008 enhanced long term potentiation "greater than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, J:81922]
Show

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Usp9xtm1Tuv/Usp9x+
Genetic Background: involves: 129S4/SvJae * FVB/N

 MP:0003635 abnormal synaptic transmission "defect in the communication from a neuron to a target across a synapse " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Usp9xtm1Tuv/Usp9x+
Genetic Background: involves: 129S4/SvJae * FVB/N

 MP:0003663 abnormal thermosensation "defect in the ability to sense or display a preference for a given temperature" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96549]
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Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Usp9xtm1Tuv/Usp9x+
Genetic Background: involves: 129S4/SvJae * FVB/N

Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004646 decreased cervical vertebrae number "reduced number of the seven bony segments of the spine located anterior to the thoracic vertebrae and caudal to the skull" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

 MP:0004753 abnormal miniature excitatory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Usp9xtm1Tuv/Usp9x+
Genetic Background: involves: 129S4/SvJae * FVB/N

 MP:0004859 abnormal synaptic plasticity "anomaly in the ability of a synapse to change its strength as a result of successive activations" [MESH:National Library of Medicine_Medical Subject Headings, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Usp9xtm1Tuv/Usp9x+
Genetic Background: involves: 129S4/SvJae * FVB/N

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

 MP:0005266 abnormal metabolism "anomalous chemical and physical changes occurring in tissue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Usp9xtm1Tuv/Usp9x+
Genetic Background: involves: 129S4/SvJae * FVB/N

 MP:0008810 increased circulating iron level "elevation in the concentration of iron in the blood" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Usp9xtm1Tuv/Usp9x+
Genetic Background: involves: 129S4/SvJae * FVB/N

 MP:0009453 enhanced contextual conditioning "increase in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and the neutral, unchanging environment (the conditioned stimulus (CS), or the environmental context in this case)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Usp9xtm1Tuv/Usp9x+
Genetic Background: involves: 129S4/SvJae * FVB/N

 MP:0009455 enhanced cued conditioning behavior "increase in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light flash)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Usp9xtm1Tuv/Usp9x+
Genetic Background: involves: 129S4/SvJae * FVB/N

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

 MP:0011954 shortened PQ interval "decrease in the length of time between the beginning of atrial depolarization and the end of atrial repolarization (or recovery), measured by the interval from the beginning of the P wave to the end of the Q wave" [MPD:Molly]
Show

Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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