ENSMUSG00000062683


Mus musculus

Features
Gene ID: ENSMUSG00000062683
  
Biological name :Atp5g2
  
Synonyms : Atp5g2 / ATP synthase F(0) complex subunit C2, mitochondrial / P56383
  
Possible biological names infered from orthology : ATP5MC2 / ATP synthase membrane subunit c locus 2 / Q06055
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: F3
Gene start: 102662864
Gene end: 102672352
  
Corresponding Affymetrix probe sets: 10433049 (MoGene1.0st)   10433055 (MoGene1.0st)   10447566 (MoGene1.0st)   10560816 (MoGene1.0st)   1415980_at (Mouse Genome 430 2.0 Array)   1447714_x_at (Mouse Genome 430 2.0 Array)   1456128_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140323
Ensembl peptide - ENSMUSP00000141008
Ensembl peptide - ENSMUSP00000140414
Ensembl peptide - ENSMUSP00000075057
NCBI entrez gene - 67942     See in Manteia.
MGI - MGI:1915192
RefSeq - NM_026468
RefSeq Peptide - NP_080744
swissprot - A0A087WSE2
swissprot - A0A087WQS5
swissprot - P56383
Ensembl - ENSMUSG00000062683
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP5MC2ENSGALG00000030086Gallus gallus
 Q06055ENSG00000135390Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P56384 / Atp5g3 / ATP synthase F(0) complex subunit C3, mitochondrial / P48201* / ATP5MC3* / ATP synthase membrane subunit c locus 3*ENSMUSG0000001877069
Q9CR84 / Atp5g1 / ATP synthase F(0) complex subunit C1, mitochondrial / P05496* / ATP5MC1* / ATP synthase membrane subunit c locus 1*ENSMUSG0000000605769


Protein motifs (from Interpro)
Interpro ID Name
 IPR000454  ATP synthase, F0 complex, subunit C
 IPR002379  V-ATPase proteolipid subunit C-like domain
 IPR020537  ATP synthase, F0 complex, subunit C, DCCD-binding site
 IPR035921  F/V-ATP synthase subunit C superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0015986 ATP synthesis coupled proton transport IBA
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 cellular_componentGO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) IBA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain IEA
 cellular_componentGO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015078 proton transmembrane transporter activity IEA
 molecular_functionGO:0046933 proton-transporting ATP synthase activity, rotational mechanism IBA


Pathways (from Reactome)
Pathway description
Formation of ATP by chemiosmotic coupling
Cristae formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0008935 decreased mean platelet volume "reduced average content of platelet cells over normal" [MGI:mberry "Melissa Berry, Genetics Resources Curator"]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0011965 decreased total retina thickness "decreased width of the retina through the center plane" [MGI:csmith]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0013279 increased fasted circulating glucose level "increase in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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