ENSMUSG00000062773


Mus musculus

Features
Gene ID: ENSMUSG00000062773
  
Biological name :Tex101
  
Synonyms : Q9JMI7 / testis expressed gene 101 / Tex101
  
Possible biological names infered from orthology : Q9BY14 / testis expressed 101
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A3
Gene start: 24668007
Gene end: 24676675
  
Corresponding Affymetrix probe sets: 10560873 (MoGene1.0st)   1449103_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000077150
Ensembl peptide - ENSMUSP00000146082
Ensembl peptide - ENSMUSP00000146186
NCBI entrez gene - 56746     See in Manteia.
MGI - MGI:1930791
RefSeq - NM_019981
RefSeq Peptide - NP_064365
swissprot - Q076U5
swissprot - Q9JMI7
Ensembl - ENSMUSG00000062773
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9BY14ENSG00000131126Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cd177 / Q8R2S8 / CD177 antigen / Q8N6Q3* / CD177 molecule*ENSMUSG0000005221226
Lypd4 / Q8BVP6 / Ly6/PLAUR domain-containing protein 4 / Q6UWN0* / LY6/PLAUR domain containing 4*ENSMUSG0000006273222
BC049730 / cDNA sequence BC049730ENSMUSG0000004558712
Gm4763ENSMUSG000000587175


Protein motifs (from Interpro)
Interpro ID Name
 IPR016054  Ly-6 antigen/uPA receptor-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007339 binding of sperm to zona pellucida IMP
 biological_processGO:0009566 fertilization IMP
 biological_processGO:0097722 sperm motility IMP
 biological_processGO:1901317 regulation of flagellated sperm motility IMP
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0002080 acrosomal membrane IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0046658 anchored component of plasma membrane IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr,Ctnnb1tm1Mmt/Ctnnb1+,Krt14tm1.1(cre)Wbm/Krt14+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ

Allelic Composition: Tex101tm1Qzh/Tex101tm1Qzh
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR)

 MP:0002674 abnormal sperm motility "anomalies in the mobility of the spermatozoa" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr,Ctnnb1tm1Mmt/Ctnnb1+,Krt14tm1.1(cre)Wbm/Krt14+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ

 MP:0004542 impaired acrosome reaction "abnormality in the cellular exocytosis that allows sperm to penetrate the zona pellucida of ovulated eggs" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr,Ctnnb1tm1Mmt/Ctnnb1+,Krt14tm1.1(cre)Wbm/Krt14+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ

 MP:0004543 abnormal sperm physiology "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr,Ctnnb1tm1Mmt/Ctnnb1+,Krt14tm1.1(cre)Wbm/Krt14+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ

Allelic Composition: Tex101tm1Qzh/Tex101tm1Qzh
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR)

 MP:0009647 decreased fertilization frequency "he number of secondary oocytes each penetrated by a spermatozoon followed by fusion of the male and female pronuclei are fewer than expected" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex101tm1Qzh/Tex101tm1Qzh
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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