ENSMUSG00000063235


Mus musculus

Features
Gene ID: ENSMUSG00000063235
  
Biological name :Ptpmt1
  
Synonyms : Ptpmt1
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: E1
Gene start: 90908716
Gene end: 90918258
  
Corresponding Affymetrix probe sets: 10484920 (MoGene1.0st)   1426581_at (Mouse Genome 430 2.0 Array)   
  
Cross references: NCBI entrez gene - 66461     See in Manteia.
MGI - MGI:1913711
Ensembl - ENSMUSG00000063235
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000333 decreased bone marrow cell number "decreased number of cells that make up the core cavities of bones when compared to the norm" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896]
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Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL

 MP:0000352 decreased cell proliferation "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Rbfox1tm1.1Dblk/Rbfox1+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * SJL

 MP:0000692 small spleen "decreased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ptpmt1tm2.1Ckq/Ptpmt1tm2.1Ckq,Tg(Vav1-cre)1Graf/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * SJL

 MP:0000706 small thymus "reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167]
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Allelic Composition: Ptpmt1tm2.1Ckq/Ptpmt1tm2.1Ckq,Tg(Vav1-cre)1Graf/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * SJL

 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
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Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL

Allelic Composition: Ptpmt1tm2.1Ckq/Ptpmt1tm2.1Ckq,Tg(Vav1-cre)1Graf/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * SJL

 MP:0001606 impaired hematopoiesis "atypical process of blood cell formation with the result of fewer of these cells being formed" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896]
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Allelic Composition: Ptpmt1tm2.1Ckq/Ptpmt1tm2.1Ckq,Tg(Vav1-cre)1Graf/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * SJL

 MP:0001697 abnormal embryo size "anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Gtpbp2tm1b(KOMP)Mbp/Gtpbp2+
Genetic Background: C57BL/6N-Gtpbp2tm1b(KOMP)Mbp/Ucd

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Myo5ad/Myo5ad-97H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0003988 disorganized embryonic tissue "a lack of the regular arrangement of any embryonic tissues" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:58080]
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Allelic Composition: Myo5ad/Myo5ad-97H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0004809 increased hematopoietic stem cell number "greater cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL

Allelic Composition: Ptpmt1tm2.1Ckq/Ptpmt1tm2.1Ckq,Tg(Vav1-cre)1Graf/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * SJL

 MP:0005152 pancytopenia "reduction in the number of erythrocytes, all types of white blood cells, and platelets in the circulating blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:20450]
Show

Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL

Allelic Composition: Ptpmt1tm2.1Ckq/Ptpmt1tm2.1Ckq,Tg(Vav1-cre)1Graf/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * SJL

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Rbfox1tm1.1Dblk/Rbfox1+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * SJL

 MP:0006035 abnormal mitochondrial morphology "anomalous structure of the mitochondria" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Rbfox1tm1.1Dblk/Rbfox1+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * SJL

 MP:0008249 abnormal common lymphocyte progenitor cell morphology "any structural anomaly of a progenitor cell committed to the lymphoid lineage" [CL:0000051, PMID:10407577]
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Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL

 MP:0008813 decreased common myeloid progenitor cell number "reduced number of progenitor cells committed to myeloid lineage, including the megakaryocyte and erythroid lineages" [CL:0000049, MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL

 MP:0010763 abnormal hematopoietic stem cell physiology "any functional anomaly or number of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; HSCs give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL

 MP:0010957 abnormal aerobic respiration "any anomaly in the process of enzymatic release of energy from organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor" [GO:0009060]
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Allelic Composition: Rbfox1tm1.1Dblk/Rbfox1+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Ptpmt1tm2.1Ckq/Ptpmt1tm2.1Ckq,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Ptpmt1tm2.1Ckq/Ptpmt1tm2.1Ckq,Tg(Vav1-cre)1Graf/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * SJL

 MP:0011095 complete embryonic lethality between implantation and placentation "death of all organisms of a given genotype in a population between the point of implantation and the initiation of placentation (Mus: E4.5 to less than E9)" [MGI:csmith]
Show

Allelic Composition: Rbfox1tm1.1Dblk/Rbfox1+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * SJL

 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
Show

Allelic Composition: Myo5ad/Myo5ad-97H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

 MP:0012114 absent inner cell mass proliferation 
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Allelic Composition: Myo5ad/Myo5ad-97H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
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Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

 MP:0013504 increased embryonic tissue cell apoptosis "increase in the timing or the number of cells in embryonic tissue undergoing programmed cell death" [MGI:csmith]
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Allelic Composition: Myo5ad/Myo5ad-97H
Genetic Background: involves: 101/H * C3H/HeH

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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