MP:0000259 | abnormal vascular development | "malformation or aberrant differentiation of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17509] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0000600 | liver hypoplasia | "reduced size of liver due to decreased cell number " [J:57631] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0000601 | small liver | "reduced size of the liver" [J:23170] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0001577 | anemia | "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0001614 | abnormal vasculature | "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0001625 | cardiac hypertrophy | "an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0001915 | intracranial hemorrhage | "bleeding within the skull, including hemorrhage into the brain and within the cranial epidural, subdural, and subarachnoid spaces" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0002152 | abnormal brain morphology | "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0003345 | decreased number of ribs | "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Casq2tm1b(KOMP)Wtsi/Casq2+ Genetic Background: C57BL/6N-Casq2tm1b(KOMP)Wtsi/Ucd
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MP:0004001 | decreased hepatocyte proliferation | "reduced growth and reproduction of hepatocyte cells of the liver" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0004259 | small placenta | "reduced size of the size or shape of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0004647 | decreased lumbar vertebrae number | "reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: Casq2tm1b(KOMP)Wtsi/Casq2+ Genetic Background: C57BL/6N-Casq2tm1b(KOMP)Wtsi/Ucd
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MP:0004950 | abnormal brain vasculature | "any structural anomaly of the blood vessel network of the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0005031 | abnormal trophoblast | "malformation of the mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and contributes to the formation of the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0010101 | increased sacral vertebrae number | "increase of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Casq2tm1b(KOMP)Wtsi/Casq2+ Genetic Background: C57BL/6N-Casq2tm1b(KOMP)Wtsi/Ucd
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MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd
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MP:0011526 | abnormal placenta fetal blood space morphology | "any structural anomaly of the spaces of the placenta occupied by fetal blood, primarily within the fetal labyrinth villi" [MGI:csmith] |
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Allelic Composition: Tg(KRT5-cre/ERT2)2Ipc/0,Upf3atm1.1Wilk/Upf3atm1.1Wilk Genetic Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
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