ENSMUSG00000068428


Mus musculus

Features
Gene ID: ENSMUSG00000068428
  
Biological name :Gmnc
  
Synonyms : geminin coiled-coil domain containing / Gmnc / Q3URY2
  
Possible biological names infered from orthology : A6NCL1
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: B2
Gene start: 26957236
Gene end: 26989974
  
Corresponding Affymetrix probe sets: 10438784 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000087269
NCBI entrez gene - 239789     See in Manteia.
MGI - MGI:2685452
RefSeq - NM_001285918
RefSeq - XM_006522113
RefSeq - NM_001013761
RefSeq - NM_001285916
RefSeq Peptide - NP_001272845
RefSeq Peptide - NP_001272847
RefSeq Peptide - NP_001013783
swissprot - Q3URY2
Ensembl - ENSMUSG00000068428
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gmncENSDARG00000068719Danio rerio
 GMNCENSGALG00000026907Gallus gallus
 GMNCENSG00000205835Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029700  Geminin coiled-coil domain-containing protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IMP
 biological_processGO:0006270 DNA replication initiation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0060271 cilium assembly IMP
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus ISS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003682 chromatin binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Commd9tm1c(KOMP)Wtsi/Commd9tm1c(KOMP)Wtsi,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: C57BL/6N

 MP:0002285 abnormal tracheal ciliated epithelium morphology "structural anomaly of the epithelial lining of the trachea which contains numerous ciliated cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology:ISBN 0-397-51047-0]
Show

Allelic Composition: Commd9tm1c(KOMP)Wtsi/Commd9tm1c(KOMP)Wtsi,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: C57BL/6N

 MP:0008489 postnatal slow weight gain "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Commd9tm1c(KOMP)Wtsi/Commd9tm1c(KOMP)Wtsi,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: C57BL/6N

 MP:0010861 increased respiratory mucosa goblet cell number "greater number of the cells of the respiratory epithelial lining that produce and secrete mucins" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Commd9tm1c(KOMP)Wtsi/Commd9tm1c(KOMP)Wtsi,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: C57BL/6N

 MP:0011054 absent respiratory motile cilia "absence of the multiple epithelial tiny, motile hair-like projections, which have a variable arrangement of axonemal microtubules, contains molecular motors, and beat with a characteristic whip-like pattern that promote transport of fluids and other cells across the epithelium of the respiratory tract" [GO:0031514, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Commd9tm1c(KOMP)Wtsi/Commd9tm1c(KOMP)Wtsi,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: C57BL/6N

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Commd9tm1c(KOMP)Wtsi/Commd9tm1c(KOMP)Wtsi,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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