Manteia

ENSMUSG00000071528

Mus musculus

Features

Gene ID:	ENSMUSG00000071528

Biological name :	Usmg5

Synonyms :	Q78IK2 / upregulated during skeletal muscle growth 5 / Usmg5

Possible biological names infered from orthology :	ATP5MD / ATP synthase membrane subunit DAPIT / Q96IX5

Species:	Mus musculus

Chr. number:	19
Strand:	-1
Band:	C3
Gene start:	47083471
Gene end:	47090625

Corresponding Affymetrix probe sets:	10468287 (MoGene1.0st) 10572813 (MoGene1.0st) 10603833 (MoGene1.0st) 1448179_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000093713 NCBI entrez gene - 66477 See in Manteia. MGI - MGI:1891435 RefSeq - NM_023211 RefSeq Peptide - NP_075700 swissprot - Q78IK2 Ensembl - ENSMUSG00000071528

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
ATP5MD	ENSDARG00000096003	Danio rerio
USMG5	ENSGALG00000034645	Gallus gallus
ATP5MD	ENSG00000173915	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR009125	DAPIT

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0008150	biological_process	ND
cellular_component	GO:0005739	mitochondrion	ISO
cellular_component	GO:0005743	mitochondrial inner membrane	IDA
cellular_component	GO:0005753	mitochondrial proton-transporting ATP synthase complex	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0031966	mitochondrial membrane	IEA
molecular_function	GO:0003674	molecular_function	ND

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000218	increased WBC count	"greater than normal WBC numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0001406	abnormal gait	"unusual or distinctive way of walking" [J:65038]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0001566	hyperphosphatemia	"abnormally high concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0002590	increased mean corpuscular volume	"greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0002968	increased circulating alkaline phosphatase level	"elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0003019	increased circulating chloride level	"elevated concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0003795	abnormal bone structure		Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0003961	decreased lean body mass	"less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0005343	increased circulating aspartate transaminase level	"greater than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0005419	hypoalbuminemia	"blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0005560	decreased circulating glucose level	"less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0005565	increased blood urea nitrogen level	"high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0005567	decreased circulating total protein level	"less than the average total concentration of these macromolecules in the blood " [RGD:Rat Genome Database submission]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0005633	increased circulating sodium level	"greater than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0010025	decreased total body fat amount	"less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0010053	decreased grip strength	"reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0010088	decreased circulating fructosamine level	"decrease in the concentration in the blood of total non enzymatic glycated proteins in the blood" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H
MP:0010124	decreased bone mineral content	"reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Txnip^{tm1b(EUCOMM)Hmgu}/Txnip^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Txnip^{tm1b(EUCOMM)Hmgu}/H

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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