ENSMUSG00000072770


Mus musculus

Features
Gene ID: ENSMUSG00000072770
  
Biological name :Acrbp
  
Synonyms : Acrbp / Acrosin-binding protein / Q3V140
  
Possible biological names infered from orthology : Q8NEB7
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: F2
Gene start: 125049689
Gene end: 125063267
  
Corresponding Affymetrix probe sets: 10541785 (MoGene1.0st)   1422874_at (Mouse Genome 430 2.0 Array)   1451333_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032481
Ensembl peptide - ENSMUSP00000085632
Ensembl peptide - ENSMUSP00000108032
Ensembl peptide - ENSMUSP00000108033
NCBI entrez gene - 54137     See in Manteia.
MGI - MGI:1859515
RefSeq - NM_016845
RefSeq - NM_001127340
RefSeq Peptide - NP_001120812
RefSeq Peptide - NP_058541
swissprot - Q6P8Q6
swissprot - Q3V140
swissprot - F2Z440
Ensembl - ENSMUSG00000072770
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000044625Gallus gallus
 ACRBPENSG00000111644Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009865  Proacrosin binding sp32
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007286 spermatid development ISA
 biological_processGO:0010952 positive regulation of peptidase activity IEA
 biological_processGO:0048240 sperm capacitation IBA
 cellular_componentGO:0001669 acrosomal vesicle ISA
 cellular_componentGO:0002080 acrosomal membrane ISS
 cellular_componentGO:0005576 extracellular region ISS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016504 peptidase activator activity ISA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Large1myd/Large1+
Genetic Background: B6C3Fe a/a-Large1myd/J

 MP:0005411 delayed fertilization "a lag in the normal time of onset of the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Large1myd/Large1+
Genetic Background: B6C3Fe a/a-Large1myd/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr