ENSMUSG00000073684


Mus musculus

Features
Gene ID: ENSMUSG00000073684
  
Biological name :Faap20
  
Synonyms : Faap20 / Fanconi anemia core complex-associated protein 20 / Q3UN58
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: E2
Gene start: 155249802
Gene end: 155256687
  
Corresponding Affymetrix probe sets: 10511007 (MoGene1.0st)   1431003_a_at (Mouse Genome 430 2.0 Array)   1438154_x_at (Mouse Genome 430 2.0 Array)   1456310_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000095354
Ensembl peptide - ENSMUSP00000101252
Ensembl peptide - ENSMUSP00000117360
Ensembl peptide - ENSMUSP00000121522
Ensembl peptide - ENSMUSP00000137116
NCBI entrez gene - 67513     See in Manteia.
MGI - MGI:1914763
RefSeq - XM_011250322
RefSeq - XM_006539119
RefSeq - NM_001190445
RefSeq - XM_011250323
RefSeq Peptide - NP_001334191
RefSeq Peptide - NP_001177374
swissprot - Q3UN58
swissprot - F6QQ55
swissprot - F2Z421
Ensembl - ENSMUSG00000073684
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR031490  FAAP20 ubiquitin-binding zinc-finger
 IPR031491  FAAP20, FANCA interaction domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IBA
 biological_processGO:0019985 translesion synthesis ISO
 biological_processGO:0036297 interstrand cross-link repair ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005694 chromosome ISO
 cellular_componentGO:0016604 nuclear body ISO
 cellular_componentGO:0030054 cell junction ISO
 cellular_componentGO:0043240 Fanconi anaemia nuclear complex IBA
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding ISS
 molecular_functionGO:0043130 ubiquitin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070530 K63-linked polyubiquitin modification-dependent protein binding IBA
 molecular_functionGO:0140036 ubiquitin-dependent protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Ildr1tm1(KOMP)Wtsi/Ildr1tm1(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0001131 abnormal ovarian follicles "malformed or absent sac-like structure in the ovary which surrounds an ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042]
Show

Allelic Composition: Ildr1tm1(KOMP)Wtsi/Ildr1tm1(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Ildr1tm1(KOMP)Wtsi/Ildr1tm1(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: Ildr1tm1(KOMP)Wtsi/Ildr1tm1(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0001545 abnormal hematopoietic system physiology "anomalous function of the fluid and/or its suspended elements that circulate(s) through the heart, arteries, capillaries, and veins" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ildr1tm1(KOMP)Wtsi/Ildr1tm1(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

Allelic Composition: Faap20tm1(KOMP)Mbp/Faap20tm1(KOMP)Mbp,Fancatm1.1Wong/Fancatm1.1Wong
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ildr1tm1(KOMP)Wtsi/Ildr1tm1(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0003077 abnormal cell cycle "failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266]
Show

Allelic Composition: Ildr1tm1(KOMP)Wtsi/Ildr1tm1(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ildr1tm1(KOMP)Wtsi/Ildr1tm1(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0005152 pancytopenia "reduction in the number of erythrocytes, all types of white blood cells, and platelets in the circulating blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:20450]
Show

Allelic Composition: Ildr1tm1(KOMP)Wtsi/Ildr1tm1(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ildr1tm1(KOMP)Wtsi/Ildr1tm1(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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