Manteia

ENSMUSG00000074064

Mus musculus

Features

Gene ID:	ENSMUSG00000074064

Biological name :	Mlycd

Synonyms :	malonyl-CoA decarboxylase / Mlycd / Q99J39

Possible biological names infered from orthology :	AC009119.2 / O95822

Species:	Mus musculus

Chr. number:	8
Strand:	1
Band:	E1
Gene start:	119394878
Gene end:	119411102

Corresponding Affymetrix probe sets:	10575867 (MoGene1.0st) 1449964_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000095970 NCBI entrez gene - 56690 See in Manteia. MGI - MGI:1928485 RefSeq - XM_006531226 RefSeq - NM_019966 RefSeq - XM_006531218 RefSeq Peptide - NP_064350 swissprot - Q99J39 Ensembl - ENSMUSG00000074064

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR007956	Malonyl-CoA decarboxylase, C-terminal
IPR035372	Malonyl-CoA decarboxylase, N-terminal

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0002931	response to ischemia	IEA
biological_process	GO:0006085	acetyl-CoA biosynthetic process	ISS
biological_process	GO:0006629	lipid metabolic process	IEA
biological_process	GO:0006631	fatty acid metabolic process	IEA
biological_process	GO:0006633	fatty acid biosynthetic process	ISO
biological_process	GO:0010906	regulation of glucose metabolic process	IEA
biological_process	GO:0019395	fatty acid oxidation	IEA
biological_process	GO:0031998	regulation of fatty acid beta-oxidation	IEA
biological_process	GO:0046320	regulation of fatty acid oxidation	IEA
biological_process	GO:0046321	positive regulation of fatty acid oxidation	ISO
biological_process	GO:2001294	malonyl-CoA catabolic process	ISO
cellular_component	GO:0005737	cytoplasm	ISS
cellular_component	GO:0005739	mitochondrion	ISO
cellular_component	GO:0005759	mitochondrial matrix	ISS
cellular_component	GO:0005777	peroxisome	ISO
cellular_component	GO:0005782	peroxisomal matrix	ISS
cellular_component	GO:0005829	cytosol	IEA
molecular_function	GO:0005102	signaling receptor binding	ISO
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0016829	lyase activity	IEA
molecular_function	GO:0016831	carboxy-lyase activity	IEA
molecular_function	GO:0042802	identical protein binding	ISO
molecular_function	GO:0050080	malonyl-CoA decarboxylase activity	ISO

Pathways (from Reactome)

Pathway description

Beta-oxidation of very long chain fatty acids

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002078	abnormal glucose homeostasis	"anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Kras^tm3Tyj/Kras^tm3Tyj Genetic Background: involves: 129S4/SvJae
MP:0002128	abnormal blood circulation	"failure or atypical movement in the flow of blood from the heart to the vasculature and back to the heart" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Kras^tm3Tyj/Kras^tm3Tyj Genetic Background: involves: 129S4/SvJae
MP:0003394	increased cardiac output	"greater than normal blood volume pumped by each ventricle per minute" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Kras^tm3Tyj/Kras^tm3Tyj Genetic Background: involves: 129S4/SvJae

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr