ENSMUSG00000074218


Mus musculus

Features
Gene ID: ENSMUSG00000074218
  
Biological name :Cox7a1
  
Synonyms : Cox7a1 / Cytochrome c oxidase subunit 7A1, mitochondrial / P56392
  
Possible biological names infered from orthology : cytochrome c oxidase subunit 7A1 / P24310
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B1
Gene start: 30184144
Gene end: 30186078
  
Corresponding Affymetrix probe sets: 10551836 (MoGene1.0st)   1418709_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146960
Ensembl peptide - ENSMUSP00000096193
NCBI entrez gene - 12865     See in Manteia.
MGI - MGI:1316714
RefSeq - NM_009944
RefSeq Peptide - NP_034074
swissprot - A0A140LIU4
swissprot - P56392
swissprot - Q792A4
Ensembl - ENSMUSG00000074218
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cox7a1ENSDARG00000069464Danio rerio
 COX7A1ENSG00000161281Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cox7a2 / P48771 / Cytochrome c oxidase subunit 7A2, mitochondrial / cytochrome c oxidase subunit 7A2*ENSMUSG0000003233058
Q61387 / Cox7a2l / Cytochrome c oxidase subunit 7A-related protein, mitochondrial / O14548* / cytochrome c oxidase subunit 7A2 like*ENSMUSG0000002424840


Protein motifs (from Interpro)
Interpro ID Name
 IPR003177  Cytochrome c oxidase, subunit VIIa
 IPR036539  Cytochrome c oxidase, subunit VIIa superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:1902600 proton transmembrane transport IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005746 mitochondrial respiratory chain IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004129 cytochrome-c oxidase activity IEA
 molecular_functionGO:0009055 electron transfer activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0001488 increased startle reflex "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Foxn1nu-2J/Foxn1nu-2J
Genetic Background: B6(SJL)-Foxn1nu-2J/GrsrJ

 MP:0002795 dilated cardiomyopathy "decreased function of the heart associated with cardiac enlargement and congestive heart failure" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Foxn1nu-2J/Foxn1nu-2J
Genetic Background: B6(SJL)-Foxn1nu-2J/GrsrJ

 MP:0003915 increased left ventricle weight "greater than average weight of the left ventricle compared to the average for a particular strain" [RGD:Rat Genome Database submission]
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Allelic Composition: Foxn1nu-2J/Foxn1nu-2J
Genetic Background: B6(SJL)-Foxn1nu-2J/GrsrJ

 MP:0005012 decreased eosinophil count "fewer than normal eosinophil numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0005598 decreased ventricle muscle contractility "reduced ability of the heart ventricle muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Foxn1nu-2J/Foxn1nu-2J
Genetic Background: B6(SJL)-Foxn1nu-2J/GrsrJ

Allelic Composition: Cox7a1tm1Hutt/Cox7a1+
Genetic Background: B6.129-Cox7a1tm1Hutt

 MP:0010954 abnormal cellular respiration "anomaly in the enzymatic release of energy from organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration)" [GO:0045333]
Show

Allelic Composition: Foxn1nu-2J/Foxn1nu-2J
Genetic Background: B6(SJL)-Foxn1nu-2J/GrsrJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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