ENSMUSG00000074874


Mus musculus

Features
Gene ID: ENSMUSG00000074874
  
Biological name :Ctla2b
  
Synonyms : Ctla2b / P12400 / Protein CTLA-2-beta
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B2
Gene start: 60895350
Gene end: 60897447
  
Corresponding Affymetrix probe sets: 10409866 (MoGene1.0st)   1416811_s_at (Mouse Genome 430 2.0 Array)   1452352_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021884
Ensembl peptide - ENSMUSP00000153559
Ensembl peptide - ENSMUSP00000153260
Ensembl peptide - ENSMUSP00000131083
NCBI entrez gene - 13025     See in Manteia.
MGI - MGI:88555
RefSeq - XM_011244472
RefSeq - NM_001145801
RefSeq - NM_007797
RefSeq Peptide - NP_001139273
RefSeq Peptide - NP_031823
swissprot - P12400
swissprot - A0A286YE78
swissprot - A0A0R4J245
swissprot - A0A286YD41
Ensembl - ENSMUSG00000074874
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC160962.1ENSMUSG0000011443298
Ctla2a / P12399 / Protein CTLA-2-alpha ENSMUSG0000004425890
CT010498.2ENSMUSG0000011463563
CT010498.1ENSMUSG0000011448713


Protein motifs (from Interpro)
Interpro ID Name
 IPR013128  Peptidase C1A
 IPR013201  Cathepsin propeptide inhibitor domain (I29)


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 molecular_functionGO:0004869 cysteine-type endopeptidase inhibitor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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