ENSMUSG00000075012


Mus musculus

Features
Gene ID: ENSMUSG00000075012
  
Biological name :Fjx1
  
Synonyms : Fjx1 / Four-jointed box protein 1 / Q8BQB4
  
Possible biological names infered from orthology : four jointed box 1 / Q86VR8
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: E2
Gene start: 102449366
Gene end: 102452499
  
Corresponding Affymetrix probe sets: 10485402 (MoGene1.0st)   1422733_at (Mouse Genome 430 2.0 Array)   1450728_at (Mouse Genome 430 2.0 Array)   1457160_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000097270
NCBI entrez gene - 14221     See in Manteia.
MGI - MGI:1341907
RefSeq - NM_010218
RefSeq Peptide - NP_034348
swissprot - Q8BQB4
Ensembl - ENSMUSG00000075012
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fjx1ENSDARG00000035873Danio rerio
 FJX1ENSGALG00000039032Gallus gallus
 FJX1ENSG00000179431Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR024868  Four-jointed box protein 1/four-jointed protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0010842 retina layer formation IGI
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Fgf15tm1.1(KOMP)Vlcg/Fgf15tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fgf15tm1.1(KOMP)Vlcg/Ucd

 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
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Allelic Composition: Fgf15tm1.1(KOMP)Vlcg/Fgf15tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fgf15tm1.1(KOMP)Vlcg/Ucd

 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
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Allelic Composition: Fat4tm1.1Hmc/Fat4tm1.1Hmc,Vangl2Lp/Vangl2+
Genetic Background: involves: 129P2/OlaHsd * A * FVB/N

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: PhbGt(BGB069)Byg/Phb+
Genetic Background: involves: 129P2/OlaHsd * C57BL

 MP:0003068 enlarged kidney "larger than average size of the kidney" [J:86005, pvb:Pierre Vanden Borre, Mouse Genome Informatics Curator]
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Allelic Composition: Fat4tm1.1Hmc/Fat4tm1.1Hmc,Vangl2Lp/Vangl2+
Genetic Background: involves: 129P2/OlaHsd * A * FVB/N

 MP:0003675 kidney cysts "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fat4tm1.1Hmc/Fat4tm1.1Hmc,Vangl2Lp/Vangl2+
Genetic Background: involves: 129P2/OlaHsd * A * FVB/N

 MP:0004017 duplex kidney "a kidney that is split into two separate collecting systems; there may be a duplex ureter or a single ureter; may present unilaterally or bilaterally" [rbabiuk:Randall Babiuk, Mouse Genome Informatics Curator]
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Allelic Composition: Fat4tm1.1Hmc/Fat4tm1.1Hmc,Fjx1tm1Awp/Fjx1tm1Awp
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * FVB/N

 MP:0006069 abnormal retinal neuronal layer morphology "malformation in any of the neuronal layers that make up the retina, including the ganglion cell, inner plexiform, inner nuclear, outer plexiform, outer nuclear layers, the inner and outer segments" [smb:Susan M Bello, Mouse Genome Informatics Curator, Gray s Anatomy:ISBN 0-914294-08-3]
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Allelic Composition: Fat3tm1.2Good/Fat3tm1.2Good,Atoh7tm3(cre)Gan/Atoh7tm3(cre)Gan
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

 MP:0008143 abnormal dendrite morphology "any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: PhbGt(BGB069)Byg/Phb+
Genetic Background: involves: 129P2/OlaHsd * C57BL

Allelic Composition: Fjx1tm1Awp/Fjx1+,Tg(Thy1-YFP)HJrs/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * CBA

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Fat4tm1.1Hmc/Fat4tm1.1Hmc,Fjx1tm1Awp/Fjx1tm1Awp
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * FVB/N

 MP:0011493 double ureter "two ureters open separately into the renal pelvis superiorly and drain separately into the urinary bladder or genital tract; if two ureteral buds arise from the Wolffian duct, a duplex kidney with complete ureteral duplication ensues" [http://emedicine.medscape.com/article/378075-overview, MGI:anna]
Show

Allelic Composition: Fat4tm1.1Hmc/Fat4tm1.1Hmc,Fjx1tm1Awp/Fjx1tm1Awp
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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