ENSMUSG00000076435


Mus musculus

Features
Gene ID: ENSMUSG00000076435
  
Biological name :Acsf2
  
Synonyms : Acsf2 / Acyl-CoA synthetase family member 2, mitochondrial / Q8VCW8
  
Possible biological names infered from orthology : acyl-CoA synthetase family member 2 / Q96CM8
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 94557102
Gene end: 94601871
  
Corresponding Affymetrix probe sets: 10390032 (MoGene1.0st)   10492426 (MoGene1.0st)   1425355_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099453
NCBI entrez gene - 264895     See in Manteia.
MGI - MGI:2388287
RefSeq - NM_153807
RefSeq Peptide - NP_722502
swissprot - Q8VCW8
Ensembl - ENSMUSG00000076435
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acsf2ENSDARG00000061201Danio rerio
 ACSF2ENSGALG00000019768Gallus gallus
 ACSF2ENSG00000167107Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acsf3 / Q3URE1 / Acyl-CoA synthetase family member 3, mitochondrial / Q4G176* / acyl-CoA synthetase family member 3*ENSMUSG0000001501619


Protein motifs (from Interpro)
Interpro ID Name
 IPR000873  AMP-dependent synthetase/ligase
 IPR020845  AMP-binding, conserved site
 IPR025110  AMP-binding enzyme, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial Fatty Acid Beta-Oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cers1tm1.1Kwi/Cers1tm1.1Kwi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005561 increased mean corpuscular hemoglobin "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Pax3Sp-2J/Pax3Sp-2J
Genetic Background: either: C3H/HeJ-Pax3Sp-2J or (involves: C3H/HeJ * C57BL/6J)

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pax3Sp-2J/Pax3Sp-2J
Genetic Background: either: C3H/HeJ-Pax3Sp-2J or (involves: C3H/HeJ * C57BL/6J)

 MP:0011275 abnormal behavioral response to light "unexpected change in the activity of an organism (in terms of movement, outward responses) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light" [GO:0009416, MGI:llw2]
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Allelic Composition: Pax3Sp-2J/Pax3Sp-2J
Genetic Background: either: C3H/HeJ-Pax3Sp-2J or (involves: C3H/HeJ * C57BL/6J)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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