ENSMUSG00000076749


Mus musculus

Features
Gene ID: ENSMUSG00000076749
  
Biological name :Tcrg-C1
  
Synonyms : Tcrg-C1
  
Possible biological names infered from orthology : T cell receptor gamma constant 1 / T cell receptor gamma constant 2 / TRGC1 / TRGC2
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A2
Gene start: 19214103
Gene end: 19217024
  
Corresponding Affymetrix probe sets: 10403821 (MoGene1.0st)   10407940 (MoGene1.0st)   1422188_s_at (Mouse Genome 430 2.0 Array)   1422189_x_at (Mouse Genome 430 2.0 Array)   1450521_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000100338
MGI - MGI:98625
swissprot - A0A075B5Z0
Ensembl - ENSMUSG00000076749
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TRGC1ENSG00000211689Homo sapiens
 TRGC2ENSG00000227191Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tcrg-C3 / TRGC1* / TRGC2* / T cell receptor gamma constant 1* / T cell receptor gamma constant 2*ENSMUSG0000009168296
Tcrg-C2 / TRGC1* / TRGC2* / T cell receptor gamma constant 1* / T cell receptor gamma constant 2*ENSMUSG0000007675292
Tcrg-C4 / TRGC1* / TRGC2* / T cell receptor gamma constant 1* / T cell receptor gamma constant 2*ENSMUSG0000007675766


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0048873 homeostasis of number of cells within a tissue IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008347 decreased gamma-delta T cell number "reduced number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149]
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Allelic Composition: Hprttm2(UAS-Bmp4)Bhr/Hprt+,Tg(Wnt1-GAL4)1Rth/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008356 abnormal gamma-delta T cell differentiation "atypical production of or inability to produce gamma-delta T cells, and/or accumulation of gamma-delta T cell precursors" [CL:0000798, ISBN:0781735149]
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Allelic Composition: Fgfr1tm1Jpa/Fgfr1tm1.1Jpa,Fgfr2tm1Dor/Fgfr2tm1.1Dor,Twist2tm1(cre)Dor/Twist2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tcrg-C1tm1.1Dhr/Tcrg-C1tm1.1Dhr
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Tcrg-C1tm1Dhr/Tcrg-C1tm1Dhr
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Tcrg-C1tm2.1Dhr/Tcrg-C1tm2.1Dhr
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0008757 abnormal T cell receptor gamma chain V-J recombination "any anomaly in the process by which V and J gene segments of the T cell receptor gamma chain are recombined" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr1tm1Jpa/Fgfr1tm1.1Jpa,Fgfr2tm1Dor/Fgfr2tm1.1Dor,Twist2tm1(cre)Dor/Twist2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tcrg-C1tm1.1Dhr/Tcrg-C1tm1.1Dhr
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Tcrdtm1Mom/Tcrdtm1Mom,Tcrg-C1tm1.1Dhr/Tcrg-C1tm1.1Dhr
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Tcrg-C1tm1Dhr/Tcrg-C1tm1Dhr
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Tcrg-C1tm2.1Dhr/Tcrg-C1tm2.1Dhr
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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