ENSMUSG00000078713


Mus musculus

Features
Gene ID: ENSMUSG00000078713
  
Biological name :Tomm5
  
Synonyms : B1AXP6 / Mitochondrial import receptor subunit TOM5 homolog / Tomm5
  
Possible biological names infered from orthology : AL513165.2 / Q8N4H5 / translocase of outer mitochondrial membrane 5
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: B1
Gene start: 45105208
Gene end: 45108114
  
Corresponding Affymetrix probe sets: 10512701 (MoGene1.0st)   10338836 (MoGene1.0st)   10340680 (MoGene1.0st)   10341364 (MoGene1.0st)   10343057 (MoGene1.0st)   10343844 (MoGene1.0st)   10344551 (MoGene1.0st)   1415733_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000103438
Ensembl peptide - ENSMUSP00000103439
Ensembl peptide - ENSMUSP00000103440
Ensembl peptide - ENSMUSP00000103437
NCBI entrez gene - 666377     See in Manteia.
NCBI entrez gene - 68512     See in Manteia.
MGI - MGI:1915762
RefSeq - NM_001099675
RefSeq - NM_001134646
RefSeq - XM_006504240
RefSeq Peptide - NP_001093145
RefSeq Peptide - NP_001128118
swissprot - B1AXP6
Ensembl - ENSMUSG00000078713
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tomm5ENSDARG00000068265Danio rerio
 ENSGALG00000026300Gallus gallus
 AL513165.2ENSG00000256966Homo sapiens
 TOMM5ENSG00000175768Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029179  Mitochondrial import receptor subunit TOM5 homologue


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006626 protein targeting to mitochondrion IC
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005742 mitochondrial outer membrane translocase complex ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008565 protein transporter activity IC


Pathways (from Reactome)
Pathway description
Pink/Parkin Mediated Mitophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000321 increased bone marrow cell number "increased number of cells that make up the core cavitites of bones when compared to the norm" [tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0001861 lung inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the lung" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0003644 thymus atrophy "wasting of the thymus resulting in reduced size " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0004007 abnormal lung vasculature "malformation or disorganization of the blood vessels of the lung" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0005011 increased eosinophil count "greater than normal eosinophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0006050 pulmonary fibrosis "formation of fibrous tissue within the lung often resulting from inflammation or injury " [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0008770 decreased survivor rate "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0010904 abnormal alveolar pore morphology "any structural anomaly of the openings in the alveolar septum that permit air flow between adjacent alveoli" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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