ENSMUSG00000084883


Mus musculus

Features
Gene ID: ENSMUSG00000084883
  
Biological name :Ccdc85c
  
Synonyms : Ccdc85c / Coiled-coil domain-containing protein 85C / E9Q6B2
  
Possible biological names infered from orthology : A6NKD9 / coiled-coil domain containing 85C
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: F1
Gene start: 108203602
Gene end: 108275425
  
Corresponding Affymetrix probe sets: 10402572 (MoGene1.0st)   1442999_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152421
Ensembl peptide - ENSMUSP00000125757
NCBI entrez gene - 668158     See in Manteia.
MGI - MGI:3644008
RefSeq - XM_006516161
RefSeq - XM_006516158
RefSeq - XM_006516159
RefSeq - XM_006516160
RefSeq - NM_001159910
RefSeq Peptide - NP_001153382
swissprot - E9Q6B2
swissprot - A0A217FL83
Ensembl - ENSMUSG00000084883
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q0P485ENSDARG00000005232Danio rerio
 Q6DHL7ENSDARG00000079555Danio rerio
 CCDC85CENSGALG00000011139Gallus gallus
 A6NKD9ENSG00000205476Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5SP85 / Ccdc85a / Coiled-coil domain-containing protein 85A / Q96PX6* / coiled-coil domain containing 85A*ENSMUSG0000003287840
Q6PDY0 / Ccdc85b / Coiled-coil domain-containing protein 85B / Q15834* / coiled-coil domain containing 85B*ENSMUSG0000009509823


Protein motifs (from Interpro)
Interpro ID Name
 IPR019359  CCDC85 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0021987 cerebral cortex development IMP
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0043296 apical junction complex IDA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
Show

Allelic Composition: Angptl4tm1Jig/Angptl4+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0000804 abnormal occipital lobe morphology "malformation or absence of the posterior part of the cerebral hemisphere" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Angptl4tm1Jig/Angptl4+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0000825 dilated lateral ventricles "increase over the normal size of the horseshoe-shaped cavities of the cerebrum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:38857]
Show

Allelic Composition: Angptl4tm1Jig/Angptl4+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0000849 abnormal cerebellum morphology "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Angptl4tm1Jig/Angptl4+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0000897 abnormal midbrain "malformation or malfunction associated with the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions, including eye movement and coordination of auditory and visual reflexes" [J:23882, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Angptl4tm1Jig/Angptl4+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Angptl4tm1Jig/Angptl4+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001915 intracranial hemorrhage "bleeding within the skull, including hemorrhage into the brain and within the cranial epidural, subdural, and subarachnoid spaces" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Angptl4tm1Jig/Angptl4+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Angptl4tm1Jig/Angptl4+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002183 gliosis "increased growth pattern of neuroglia in a damaged area of the brain or spinal cord" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Angptl4tm1Jig/Angptl4+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002958 aqueductal stenosis "the most common form of obstructive hydrocephaly and results from narrowing of the aqueduct of Sylvius, which connects the third and fourth ventricles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Angptl4tm1Jig/Angptl4+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0003632 abnormal nervous system morphology 
Show

Allelic Composition: Angptl4tm1Jig/Angptl4+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0003633 abnormal nervous system physiology 
Show

Allelic Composition: Angptl4tm1Jig/Angptl4+
Genetic Background: involves: 129/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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