ENSMUSG00000085925


Mus musculus

Features
Gene ID: ENSMUSG00000085925
  
Biological name :Rtl1
  
Synonyms : Q7M732 / retrotransposon Gaglike 1 / Rtl1
  
Possible biological names infered from orthology : A6NKG5 / retrotransposon Gag like 1
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: F1
Gene start: 109589193
Gene end: 109600330
  
Corresponding Affymetrix probe sets: 10402606 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000115957
NCBI entrez gene - 353326     See in Manteia.
MGI - MGI:2656842
RefSeq - NM_184109
RefSeq Peptide - NP_908998
swissprot - B4YB44
swissprot - Q7M732
Ensembl - ENSMUSG00000085925
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR762395.1ENSDARG00000109342Danio rerio
 RTL1ENSG00000254656Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Peg10 / Q7TN75 / Mus musculus paternally expressed 10 (Peg10), transcript variant 1, mRNA. / Q86TG7* / paternally expressed 10*ENSMUSG000000920354


Protein motifs (from Interpro)
Interpro ID Name
 IPR021109  Aspartic peptidase domain superfamily
 IPR032549  Domain of unknown function DUF4939
 IPR032567  LDOC1-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001712 abnormal placental development "malformed or incomplete differentiation of the organ of metabolic exchange between the fetus and mother" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

 MP:0001716 abnormal placental labyrinth "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

 MP:0004201 fetal growth retardation "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

 MP:0004258 abnormal placenta size "anomaly in the size or shape of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

 MP:0004260 enlarged placenta "increased size of the size or shape of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

 MP:0004272 abnormal basement membrane morphology "anomaly in the structure, organization and/or placement of the extracellular supportive tissue adjacent to the basal surface of the epithelia, including the epithelium of muscle cells, fat cells and Schwann cells; it is comprised of type IV collagen, laminin, and sulfated proteoglycans and other components and consists of two layers, the basal lamina and the lamina reticularis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A10.272.220]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

 MP:0004920 increased placenta weight "increase in the weight of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

 MP:0004921 decreased placenta weight "reduction in the weight of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

 MP:0005031 abnormal trophoblast "malformation of the mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and contributes to the formation of the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

 MP:0006372 impaired placental function "reduction in the ability of the placenta to supply nutrients or remove waste" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

 MP:0008770 decreased survivor rate "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

Allelic Composition: Rtl1tm1Fuis/Rtl1+
Genetic Background: involves: 129S/SvEv * DBA/2

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Rtl1tm1Fuis/Rtl1+
Genetic Background: involves: 129S/SvEv * DBA/2

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: 129/Sv

Allelic Composition: Rtl1tm1Fuis/Rtl1+
Genetic Background: involves: 129S/SvEv * DBA/2

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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