ENSMUSG00000085957


Mus musculus

Features
Gene ID: ENSMUSG00000085957
  
Biological name :Syna
  
Synonyms : Q5G5D5 / Syna / Syncytin-A Surface protein Transmembrane protein
  
Possible biological names infered from orthology : endogenous retrovirus group FRD member 1, envelope / ERVFRD-1 / P60508
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G2
Gene start: 134558146
Gene end: 134560171
  
Corresponding Affymetrix probe sets: 10534301 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000116437
NCBI entrez gene - 214292     See in Manteia.
MGI - MGI:2684898
RefSeq - XM_017320789
RefSeq - NM_001013751
RefSeq - XM_011240875
RefSeq - XM_011240877
RefSeq - XM_006504404
RefSeq - XM_006504406
RefSeq - XM_011240874
RefSeq Peptide - NP_001013773
swissprot - Q5G5D5
Ensembl - ENSMUSG00000085957
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P60508ENSG00000244476Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BI41 / Gm27179 / Syncytin-B Surface protein Transmembrane protein / P60508* / ERVFRD-1* / endogenous retrovirus group FRD member 1, envelope*ENSMUSG0000009877363
Synb / Q8BI41 / Syncytin-B Surface protein Transmembrane protein / P60508* / ERVFRD-1* / endogenous retrovirus group FRD member 1, envelope*ENSMUSG0000004797763
Gm14226ENSMUSG0000008489716
BC035947 / cDNA sequence BC035947ENSMUSG0000009048614


Protein motifs (from Interpro)
Interpro ID Name
 IPR018154  TLV/ENV coat polyprotein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000768 syncytium formation by plasma membrane fusion IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0060711 labyrinthine layer development IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001716 abnormal placental labyrinth "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171]
Show

Allelic Composition: Mrgprdtm1Mjz/Mrgprdtm1Mjz
Genetic Background: B6.129S1-Mrgprdtm1Mjz

Allelic Composition: Synatm1.1Ics/Synatm1.1Ics
Genetic Background: involves: 129S2/SvPas

 MP:0003229 abnormal vitelline vasculature "malformation in the vessels of the yolk sac" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93257]
Show

Allelic Composition: Mrgprdtm1Mjz/Mrgprdtm1Mjz
Genetic Background: B6.129S1-Mrgprdtm1Mjz

 MP:0003717 pallor "an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Mrgprdtm1Mjz/Mrgprdtm1Mjz
Genetic Background: B6.129S1-Mrgprdtm1Mjz

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mrgprdtm1Mjz/Mrgprdtm1Mjz
Genetic Background: B6.129S1-Mrgprdtm1Mjz

 MP:0004265 abnormal placental transport "anomaly in the conveyance of metabolic products and nutrients across the placenta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mrgprdtm1Mjz/Mrgprdtm1Mjz
Genetic Background: B6.129S1-Mrgprdtm1Mjz

 MP:0009397 increased trophoblast giant cell number "greater than normal number of cells of the extraembryonic cell layer that contributes to the placenta" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Mrgprdtm1Mjz/Mrgprdtm1Mjz
Genetic Background: B6.129S1-Mrgprdtm1Mjz

 MP:0009429 decreased embryo weight "reduced weight of an embryo compared to littermates or other controls (sensu Mus: up to E14, or the completion of organogenesis)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mrgprdtm1Mjz/Mrgprdtm1Mjz
Genetic Background: B6.129S1-Mrgprdtm1Mjz

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Mrgprdtm1Mjz/Mrgprdtm1Mjz
Genetic Background: B6.129S1-Mrgprdtm1Mjz

Allelic Composition: Synatm1.1Ics/Synatm1.1Ics,Synbtm1.2Ics/Synbtm1.2Ics
Genetic Background: involves: 129/Sv * 129S2/SvPas * BALB/c * C57BL/6

 MP:0011099 complete lethality throughout fetal growth and development "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Synatm1.1Ics/Synatm1.1Ics
Genetic Background: involves: 129S2/SvPas

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Synatm1.1Ics/Synatm1.1Ics
Genetic Background: involves: 129S2/SvPas

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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