ENSMUSG00000089911


Mus musculus

Features
Gene ID: ENSMUSG00000089911
  
Biological name :Mfsd14a
  
Synonyms : Hippocampus abundant transcript 1 protein / Mfsd14a / P70187
  
Possible biological names infered from orthology : major facilitator superfamily domain containing 14A / Q96MC6
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: G1
Gene start: 116631164
Gene end: 116662677
  
Corresponding Affymetrix probe sets: 10501676 (MoGene1.0st)   1423195_at (Mouse Genome 430 2.0 Array)   1450898_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029570
NCBI entrez gene - 15247     See in Manteia.
MGI - MGI:1201609
RefSeq - XM_011240023
RefSeq - NM_008246
RefSeq - XM_006501030
RefSeq - XM_006501031
RefSeq Peptide - NP_032272
swissprot - P70187
Ensembl - ENSMUSG00000089911
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hiat1bENSDARG00000043055Danio rerio
 MFSD14AENSGALG00000005329Gallus gallus
 Q96MC6ENSG00000156875Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8CIA9 / Mfsd14b / Hippocampus abundant transcript-like protein 1 / Q5SR56* / major facilitator superfamily domain containing 14B*ENSMUSG0000003821270
Gm43191ENSMUSG0000010510329


Protein motifs (from Interpro)
Interpro ID Name
 IPR001958  Tetracycline resistance protein TetA/multidrug resistance protein MdtG
 IPR005829  Sugar transporter, conserved site
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055085 transmembrane transport IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005215 transporter activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Stat1tm1Rds/Stat1tm1Rds
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Stat1tm1Rds/Stat1tm1Rds
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac

 MP:0001932 abnormal spermiogenesis "failure of sperm cells to form or differentiate" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Stat1tm1Rds/Stat1tm1Rds
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac

 MP:0002686 globozoospermia "malformation of the acrosome resulting in a round sperm head" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Stat1tm1Rds/Stat1tm1Rds
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Stat1tm1Rds/Stat1tm1Rds
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac

 MP:0004910 decreased seminal gland weight "reduction in the weight of one or both of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Stat1tm1Rds/Stat1tm1Rds
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac

 MP:0008839 absent acrosome "mature spermatozoa lack the cap-like structure at the anterior end of the sperm head that produces enzymes needed for egg penetration" [MESH:A05.360.490.890.820.100, MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Stat1tm1Rds/Stat1tm1Rds
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac

 MP:0009230 abnormal sperm head morphology "any structural abnormality of the head segment of the sperm cell which contains the nucleus with densely coiled chromatin fibers, and is surrounded anteriorly by the acrosome which contains enzymes used for penetrating the female egg" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Stat1tm1Rds/Stat1tm1Rds
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac

 MP:0009833 absent sperm mitochondrial sheath "absence of the tightly packed helical sheath of ATP-producing mitochondria, normally found in the midpiece of the sperm flagellum" [PMID:14581499]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Stat1tm1Rds/Stat1tm1Rds
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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