ENSMUSG00000090223


Mus musculus

Features
Gene ID: ENSMUSG00000090223
  
Biological name :Pcp4
  
Synonyms : Calmodulin regulator protein PCP4 / P63054 / Pcp4
  
Possible biological names infered from orthology : P48539 / Purkinje cell protein 4
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: C4
Gene start: 96467606
Gene end: 96525793
  
Corresponding Affymetrix probe sets: 10437205 (MoGene1.0st)   1460214_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000062539
NCBI entrez gene - 18546     See in Manteia.
MGI - MGI:97509
RefSeq - NM_008791
RefSeq Peptide - NP_032817
swissprot - P63054
Ensembl - ENSMUSG00000090223
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PCP4 (1 of many)ENSDARG00000110729Danio rerio
 pcp4aENSDARG00000053130Danio rerio
 PCP4ENSGALG00000022819Gallus gallus
 PCP4ENSG00000183036Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR033236  Purkinje cell protein 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0099004 calmodulin dependent kinase signaling pathway IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005516 calmodulin binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000823 abnormal lateral ventricle morphology "malformation or absence of cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube; they are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

 MP:0002804 abnormal motor learning "defects in the ability to repeat a motor task requiring well coordinated movements and balance; measures cerebellar dependent learning" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Mir140tm1.1Tkob/Mir140tm1.1Tkob,Pdgfratm8Sor/Pdgfratm8Sor,Tg(Col2a1-cre)1Rsjo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

 MP:0004859 abnormal synaptic plasticity "anomaly in the ability of a synapse to change its strength as a result of successive activations" [MESH:National Library of Medicine_Medical Subject Headings, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Mir140tm1.1Tkob/Mir140tm1.1Tkob,Pdgfratm8Sor/Pdgfratm8Sor,Tg(Col2a1-cre)1Rsjo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

 MP:0005238 increased brain size "larger than the normal physical proportions of the brain" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:57958]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

 MP:0011069 abnormal brain ependyma motile cilium physiology "any functional anomaly of the tiny, motile hair-like projections from the epithelial cells that line the ventricles in the brain, which beat in concert and to move cerebrospinal fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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