ENSMUSG00000096458


Mus musculus

Features
Gene ID: ENSMUSG00000096458
  
Biological name :Moap1
  
Synonyms : Moap1 / Modulator of apoptosis 1 / Q9ERH6
  
Possible biological names infered from orthology : Q96BY2
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: E
Gene start: 102742230
Gene end: 102743661
  
Corresponding Affymetrix probe sets: 10402294 (MoGene1.0st)   1448787_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133459
Ensembl peptide - ENSMUSP00000137010
NCBI entrez gene - 64113     See in Manteia.
MGI - MGI:1915555
RefSeq - NM_001142937
RefSeq - NM_022323
RefSeq Peptide - NP_001136409
RefSeq Peptide - NP_071718
swissprot - Q9ERH6
Ensembl - ENSMUSG00000096458
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MOAP1ENSG00000165943Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pnma1 / Q8C1C8 / Paraneoplastic antigen Ma1 homolog / Q8ND90* / PNMA family member 1*ENSMUSG0000005438355
Pnma3 / Q8JZW8 / Paraneoplastic antigen Ma3 homolog / Q9UL41* / PNMA family member 3*ENSMUSG0000004628740
Pnma5 / Q5DTT8 / Paraneoplastic antigen-like protein 5 / Q96PV4* / PNMA family member 5*ENSMUSG0000005042439
Pnma2 / Q8BHK0 / Paraneoplastic antigen Ma2 homolog / Q9UL42* / PNMA family member 2*ENSMUSG0000004620439
Gm18336 / PNMA6E* / PNMA6F* / A0A0J9YX94* / A0A0J9YXQ4* / PNMA family member 6E* / PNMA family member 6F*ENSMUSG0000009696634
Pnmal1 / Q80VM8 / Paraneoplastic antigen-like protein 8A / Q86V59* / PNMA8A* / PNMA family member 8A*ENSMUSG0000004114123
Q9CZA5 / Zcchc12 / zinc finger, CCHC domain containing 12 / P0CG32* / ZCCHC18* / zinc finger CCHC-type containing 18*ENSMUSG0000003669921
Q8VD24 / Zcchc18 / zinc finger, CCHC domain containing 18 / P0CG32* / zinc finger CCHC-type containing 18*ENSMUSG0000003142821
Gm42372 / PNMA family member 8C / PNMA8C* / A0A1B0GUJ8*ENSMUSG0000010834816
Pnmal2 / PNMA-like 2 / PNMA8B* / Q9ULN7* / PNMA family member 8B*ENSMUSG0000007080216
Gm45015 / PNMA6E* / PNMA6F* / A0A0J9YX94* / A0A0J9YXQ4* / PNMA family member 6E* / PNMA family member 6F*ENSMUSG0000010936813


Protein motifs (from Interpro)
Interpro ID Name
 IPR026523  Paraneoplastic antigen Ma


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway ISO
 biological_processGO:0006915 apoptotic process RCA
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors ISO
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage ISO
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0090200 positive regulation of release of cytochrome c from mitochondria ISO
 biological_processGO:0097190 apoptotic signaling pathway ISO
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005741 mitochondrial outer membrane ISO
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008891 decreased hepatocyte apoptosis "reduction in the number of hepatocytes undergoing programmed cell death" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Ryr2tm3.1Hhv/Ryr2+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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