ENSMUSG00000102037


Mus musculus

Features
Gene ID: ENSMUSG00000102037
  
Biological name :Bcl2a1a
  
Synonyms : Bcl2a1a / Bcl-2-related protein A1 / Q07440
  
Possible biological names infered from orthology : BCL2A1 / Q16548 / Q9HBF5 / ST20 / suppressor of tumorigenicity 20
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: E3.1
Gene start: 88956900
Gene end: 88962419
  
Corresponding Affymetrix probe sets: 10587683 (MoGene1.0st)   10587690 (MoGene1.0st)   10595633 (MoGene1.0st)   1419004_s_at (Mouse Genome 430 2.0 Array)   1437913_at (Mouse Genome 430 2.0 Array)   1450812_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000096086
NCBI entrez gene - 12044     See in Manteia.
MGI - MGI:102687
RefSeq - NM_009742
RefSeq Peptide - NP_033872
swissprot - Q07440
Ensembl - ENSMUSG00000102037
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BCL2A1ENSGALG00000006511Gallus gallus
 BCL2A1ENSG00000140379Homo sapiens
 ST20ENSG00000180953Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Bcl2a1d / B cell leukemia/lymphoma 2 related protein A1d / ST20* / BCL2A1* / Q16548* / Q9HBF5* / BCL2 related protein A1* / suppressor of tumorigenicity 20*ENSMUSG0000009997497
Bcl2a1b / B cell leukemia/lymphoma 2 related protein A1b / ST20* / BCL2A1* / Q16548* / Q9HBF5* / BCL2 related protein A1* / suppressor of tumorigenicity 20*ENSMUSG0000008992995
Gm29094 / ST20* / BCL2A1* / Q16548* / Q9HBF5* / BCL2 related protein A1* / suppressor of tumorigenicity 20*ENSMUSG0000010083879
Bcl2a1c / B cell leukemia/lymphoma 2 related protein A1c / ST20* / BCL2A1* / Q16548* / Q9HBF5* / BCL2 related protein A1* / suppressor of tumorigenicity 20*ENSMUSG0000005382057


Protein motifs (from Interpro)
Interpro ID Name
 IPR002475  Bcl2-like
 IPR013282  Bcl-2-related protein A1
 IPR020717  Apoptosis regulator, Bcl-2, BH1 motif, conserved site
 IPR020726  Apoptosis regulator, Bcl-2, BH2 motif, conserved site
 IPR026298  Blc2 family
 IPR036834  Blc2-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001782 B cell homeostasis IDA
 biological_processGO:0001836 release of cytochrome c from mitochondria IBA
 biological_processGO:0002903 negative regulation of B cell apoptotic process IDA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008053 mitochondrial fusion IBA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IBA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015267 channel activity IBA
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000418 patchy hair "uneven spots of hair growth on the body" [J:26975]
Show

Allelic Composition: Bcl2tm1Mpin/Bcl2tm1Mpin
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001876 decreased inflammatory response "less than expected response to injury, infection, or insult" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gja8tm1(Gja3)Tww/Gja8tm1(Gja3)Tww
Genetic Background: involves: 129S/SvEv

 MP:0002463 abnormal neutrophil physiology "abnormal function of these granular leukocytes, which stain with neutral dyes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Bcl2tm1Mpin/Bcl2tm1Mpin
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Bcl2a1atm1Prys/Bcl2a1atm1Prys
Genetic Background: involves: 129/Sv * C57BL/6J * SJL

 MP:0005026 decreased susceptibility to parasitic infection "reduced likelihood that an organism will develop ill effects from a parasitic infection or from components of or toxins produced by parasites " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Bcl2a1atm1Prys/Bcl2a1atm1Prys
Genetic Background: involves: 129/Sv * C57BL/6J * SJL

 MP:0009764 decreased sensitivity to induced morbidity/mortality "increase in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Bcl2a1atm1Prys/Bcl2a1atm1Prys
Genetic Background: involves: 129/Sv * C57BL/6J * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr