ENSDARG00000004830


Danio rerio

Features
Gene ID: ENSDARG00000004830
  
Biological name :flot2a
  
Synonyms : flot2a / flotillin 2a / Q98TZ8
  
Possible biological names infered from orthology : FLOT2 / flotillin 2 / Q14254 / Q60634
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 42835082
Gene end: 42872712
  
Corresponding Affymetrix probe sets: Dr.17863.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000011656
Ensembl peptide - ENSDARP00000125112
NCBI entrez gene - 245698     See in Manteia.
swissprot - F8W5F7
swissprot - Q98TZ8
ZFIN ID - ZDB-GENE-020430-3
Ensembl - ENSDARG00000004830
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FLOT2ENSGALG00000031216Gallus gallus
 FLOT2ENSG00000132589Homo sapiens
 Flot2ENSMUSG00000061981Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
flot2b / flotillin 2b / FLOT2* / Q60634* / Q14254* / flotillin 2*ENSDARG0000006977489
flot1b / flotillin 1b / FLOT1* / O75955* / O08917* / flotillin 1*ENSDARG0000003799846
flot1a / flot1b / flotillin 1b / FLOT1* / O75955* / O08917* / flotillin 1*ENSDARG0000000171044


Protein motifs (from Interpro)
Interpro ID Name
 IPR001107  Band 7 domain
 IPR027705  Flotillin family
 IPR031905  Flotillin, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:1904086 regulation of epiboly involved in gastrulation with mouth forming second IMP
 biological_processGO:2000047 regulation of cell-cell adhesion mediated by cadherin IMP
 cellular_componentGO:0005768 endosome ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030139 endocytic vesicle ISS
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Synaptic adhesion-like molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure amount , ameliorated
anatomical structure decreased amount , abnormal
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 ZFA:0000093 blastomere blastomere organization quality , abnormal
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 ZFA:0000711 DEL DEL cell-cell junction decreased amount , abnormal
DEL cell migration involved in gastrulation delayed , abnormal
DEL cell migration involved in gastrulation process quality , abnormal
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 ZFA:0001058 caudal fin caudal fin morphology , abnormal
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 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000039500 LRFN3 / zmp:0000001073 / Q8BLY3* / Q9BTN0* / leucine rich repeat and fibronectin type III domain containing 3* / Leucine-rich repeat and fibronectin type-III domain-containing protein 3 *  / complex / reaction






 

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