ENSDARG00000006963


Danio rerio
proteinmembranecse1lplasmanucleuscseexporttransportnuclearbindinggutimportin-betan-terminaldomaincasc-terminalarmadillo-likehelicalexportinimportin-likearmadillo-typefoldimportintracellularbodyfluidsecretionenvelopecytoplasmcytosol

Features
Gene ID: ENSDARG00000006963
  
Biological name :cse1l
  
Synonyms : CSE1 chromosome segregation 1-like (yeast) / cse1l / Q7SZC2
  
Possible biological names infered from orthology : chromosome segregation 1 like / Exportin-2 / P55060 / Q9ERK4
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 5468629
Gene end: 5493191
  
Corresponding Affymetrix probe sets: Dr.53.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000022858
swissprot - Q7SZC2
ZFIN ID - ZDB-GENE-990603-1
Ensembl - ENSDARG00000006963
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CSE1LENSGALG00000004707Gallus gallus
 CSE1LENSG00000124207Homo sapiens
 Cse1lENSMUSG00000002718Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001494  Importin-beta, N-terminal domain
 IPR005043  CAS/CSE, C-terminal
 IPR011989  Armadillo-like helical
 IPR013713  Exportin/Importin, Cse1-like
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
macromolecule localizationestablishment of localizationcellular localizationregulation of biological qualitymacromolecule localizationestablishment of localizationcellular localizationregulation of biological qualitymacromolecule localizationestablishment of localizationcellular localizationregulation of biological qualitymacromolecule localizationestablishment of localizationcellular localizationregulation of biological qualitymacromolecule localizationestablishment of localizationcellular localizationregulation of biological qualitymacromolecule localizationestablishment of localizationcellular localizationregulation of biological qualitymacromolecule localizationestablishment of localizationcellular localizationregulation of biological qualitymacromolecule localizationestablishment of localizationcellular localizationregulation of biological qualitymacromolecule localizationestablishment of localizationcellular localizationregulation of biological qualitymacromolecule localizationestablishment of localizationcellular localizationregulation of biological qualitymacromolecule localizationmacromolecule localizationestablishment of localizationestablishment of localizationcellular localizationcellular localizationregulation of biological qualityregulation of biological quality
nucleocytoplasmic carrier activityprotein bindingnucleocytoplasmic carrier activityprotein bindingnucleocytoplasmic carrier activityprotein bindingnucleocytoplasmic carrier activityprotein bindingnucleocytoplasmic carrier activityprotein bindingnucleocytoplasmic carrier activityprotein bindingnucleocytoplasmic carrier activityprotein bindingnucleocytoplasmic carrier activityprotein bindingnucleocytoplasmic carrier activityprotein bindingnucleocytoplasmic carrier activityprotein bindingnucleocytoplasmic carrier activitynucleocytoplasmic carrier activityprotein bindingprotein binding
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0006611 protein export from nucleus IBA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007589 body fluid secretion IMP
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009925 basal plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0016328 lateral plasma membrane IEA
 molecular_functionGO:0005049 nuclear export signal receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008536 Ran GTPase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000112 gut gut swollen , abnormal
Show

 ZFA:0000123 liver liver decreased size , abnormal
liver immature , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas degenerate , abnormal
Show

 ZFA:0005123 gut epithelium gut epithelium flattened , abnormal
Show

 ZFA:0005125 intestinal villus intestinal villus flattened , abnormal
Show

 ZFA:0009269 enterocyte enterocyte decreased height , abnormal
enterocyte microvillus decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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